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USP18-YWHAH Gene Fusion FISH Probe

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Catalog: GFFP-USP18/YWHAH-13005
Classification: Gene Fusion FISH Probes
Description: The USP18-YWHAH Gene Fusion FISH Probecan detect the fusion of USP18 and YWHAH genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: USP18-YWHAH Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase Activation Protein Eta
Gene Summary 1 This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]
Chromosome 1 Chromosome 22
Locus 1 22q12.3
Coordinates 1 This gene maps to 32340478-32353590 in GRCh37 coordinates.
Gene Name 2 Ubiquitin Specific Peptidase 18
Gene Summary 2 The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011]
Chromosome 2 Chromosome22
Locus 2 22q11.21
Coordinates 2 This gene maps to 18632757-18660162 in GRCh37 coordinates.
Associated Diseases Skin Cutaneous Melanoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-USP18/YWHAH-13005-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-USP18/YWHAH-13005-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-USP18/YWHAH-13005-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-USP18/YWHAH-13005-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-USP18/YWHAH-13005-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-USP18/YWHAH-13005-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-USP18/YWHAH-13005-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-USP18/YWHAH-13005-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-USP18/YWHAH-13005-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-USP18/YWHAH-13005-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-USP18/YWHAH-13005-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-USP18/YWHAH-13005-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-USP18/YWHAH-13005-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-USP18/YWHAH-13005-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-USP18/YWHAH-13005-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-USP18/YWHAH-13005-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-USP18/YWHAH-13005-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-USP18/YWHAH-13005-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-USP18/YWHAH-13005-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-USP18/YWHAH-13005-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-USP18/YWHAH-13005-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-USP18/YWHAH-13005-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-USP18/YWHAH-13005-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-USP18/YWHAH-13005-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-USP18/YWHAH-13005-AQAQ 467nm;467nm 418nm;418nm

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