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UHRF1-ACTA2 Gene Fusion FISH Probe

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Catalog: GFFP-UHRF1/ACTA2-12766
Classification: Gene Fusion FISH Probes
Description: The UHRF1-ACTA2 Gene Fusion FISH Probecan detect the fusion of UHRF1 and ACTA2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: UHRF1-ACTA2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Actin, Alpha 2, Smooth Muscle, Aorta
Gene Summary 1 This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017]
Chromosome 1 Chromosome 10
Locus 1 10q23.31
Coordinates 1 This gene maps to 90694830-90751147 in GRCh37 coordinates.
Gene Name 2 Ubiquitin Like With PHD And Ring Finger Domains 1
Gene Summary 2 This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. [provided by RefSeq, Feb 2014]
Chromosome 2 Chromosome19
Locus 2 19p13.3
Coordinates 2 This gene maps to 4909509-4962165 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-UHRF1/ACTA2-12766-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-UHRF1/ACTA2-12766-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-UHRF1/ACTA2-12766-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-UHRF1/ACTA2-12766-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-UHRF1/ACTA2-12766-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-UHRF1/ACTA2-12766-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-UHRF1/ACTA2-12766-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-UHRF1/ACTA2-12766-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-UHRF1/ACTA2-12766-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-UHRF1/ACTA2-12766-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-UHRF1/ACTA2-12766-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-UHRF1/ACTA2-12766-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-UHRF1/ACTA2-12766-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-UHRF1/ACTA2-12766-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-UHRF1/ACTA2-12766-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-UHRF1/ACTA2-12766-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-UHRF1/ACTA2-12766-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-UHRF1/ACTA2-12766-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-UHRF1/ACTA2-12766-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-UHRF1/ACTA2-12766-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-UHRF1/ACTA2-12766-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-UHRF1/ACTA2-12766-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-UHRF1/ACTA2-12766-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-UHRF1/ACTA2-12766-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-UHRF1/ACTA2-12766-AQAQ 467nm;467nm 418nm;418nm

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