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UBE3A-CYP19A1 Gene Fusion FISH Probe

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Catalog: GFFP-UBE3A/CYP19A1-12819
Classification: Gene Fusion FISH Probes
Description: The UBE3A-CYP19A1 Gene Fusion FISH Probecan detect the fusion of UBE3A and CYP19A1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: UBE3A-CYP19A1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Cytochrome P450 Family 19 Subfamily A Member 1
Gene Summary 1 This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]
Chromosome 1 Chromosome 15
Locus 1 15q21.2
Coordinates 1 This gene maps to 51500253-51630795 in GRCh37 coordinates.
Gene Name 2 Ubiquitin Protein Ligase E3A
Gene Summary 2 This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome15
Locus 2 15q11.2
Coordinates 2 This gene maps to 25582395-25684175 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-UBE3A/CYP19A1-12819-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-UBE3A/CYP19A1-12819-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-UBE3A/CYP19A1-12819-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-UBE3A/CYP19A1-12819-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-UBE3A/CYP19A1-12819-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-UBE3A/CYP19A1-12819-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-UBE3A/CYP19A1-12819-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-UBE3A/CYP19A1-12819-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-UBE3A/CYP19A1-12819-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-UBE3A/CYP19A1-12819-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-UBE3A/CYP19A1-12819-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-UBE3A/CYP19A1-12819-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-UBE3A/CYP19A1-12819-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-UBE3A/CYP19A1-12819-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-UBE3A/CYP19A1-12819-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-UBE3A/CYP19A1-12819-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-UBE3A/CYP19A1-12819-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-UBE3A/CYP19A1-12819-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-UBE3A/CYP19A1-12819-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-UBE3A/CYP19A1-12819-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-UBE3A/CYP19A1-12819-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-UBE3A/CYP19A1-12819-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-UBE3A/CYP19A1-12819-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-UBE3A/CYP19A1-12819-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-UBE3A/CYP19A1-12819-AQAQ 467nm;467nm 418nm;418nm

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