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UBE2E3-TECPR2 Gene Fusion FISH Probe

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Catalog: GFFP-UBE2E3/TECPR2-12840
Classification: Gene Fusion FISH Probes
Description: The UBE2E3-TECPR2 Gene Fusion FISH Probecan detect the fusion of UBE2E3 and TECPR2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: UBE2E3-TECPR2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Tectonin Beta-propeller Repeat Containing 2
Gene Summary 1 The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family, and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains. This gene has been implicated in autophagy, as reduced expression levels of this gene have been associated with impaired autophagy. Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP). HSP is characterized by progressive spasticity and paralysis of the legs. There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR), which results in inflammation of the choroid and retina. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Chromosome 1 Chromosome 14
Locus 1 14q32.31
Coordinates 1 This gene maps to 102829299-102968818 in GRCh37 coordinates.
Gene Name 2 Ubiquitin Conjugating Enzyme E2 E3
Gene Summary 2 The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2013]
Chromosome 2 Chromosome2
Locus 2 2q31.3
Coordinates 2 This gene maps to 181845111-181928150 in GRCh37 coordinates.
Associated Diseases Skin Cutaneous Melanoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-UBE2E3/TECPR2-12840-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-UBE2E3/TECPR2-12840-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-UBE2E3/TECPR2-12840-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-UBE2E3/TECPR2-12840-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-UBE2E3/TECPR2-12840-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-UBE2E3/TECPR2-12840-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-UBE2E3/TECPR2-12840-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-UBE2E3/TECPR2-12840-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-UBE2E3/TECPR2-12840-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-UBE2E3/TECPR2-12840-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-UBE2E3/TECPR2-12840-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-UBE2E3/TECPR2-12840-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-UBE2E3/TECPR2-12840-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-UBE2E3/TECPR2-12840-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-UBE2E3/TECPR2-12840-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-UBE2E3/TECPR2-12840-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-UBE2E3/TECPR2-12840-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-UBE2E3/TECPR2-12840-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-UBE2E3/TECPR2-12840-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-UBE2E3/TECPR2-12840-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-UBE2E3/TECPR2-12840-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-UBE2E3/TECPR2-12840-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-UBE2E3/TECPR2-12840-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-UBE2E3/TECPR2-12840-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-UBE2E3/TECPR2-12840-AQAQ 467nm;467nm 418nm;418nm

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