UBE2D2-ARHGAP26 Gene Fusion FISH Probe
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Catalog: |
GFFP-UBE2D2/ARHGAP26-12850 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The UBE2D2-ARHGAP26 Gene Fusion FISH Probecan detect the fusion of UBE2D2 and ARHGAP26 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
UBE2D2-ARHGAP26 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Ubiquitin Conjugating Enzyme E2 D2 |
Gene Summary 1 |
Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013] |
Chromosome 1 |
Chromosome 5 |
Locus 1 |
5q31.2 |
Coordinates 1 |
This gene maps to 138940750-139008018 in GRCh37 coordinates. |
Gene Name 2 |
Rho GTPase Activating Protein 26 |
Gene Summary 2 |
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017] |
Chromosome 2 |
Chromosome5 |
Locus 2 |
5q31.3 |
Coordinates 2 |
This gene maps to 142150291-142608572 in GRCh37 coordinates. |
Associated Diseases |
Lung Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-UBE2D2/ARHGAP26-12850-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-UBE2D2/ARHGAP26-12850-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-UBE2D2/ARHGAP26-12850-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-UBE2D2/ARHGAP26-12850-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-UBE2D2/ARHGAP26-12850-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-UBE2D2/ARHGAP26-12850-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-UBE2D2/ARHGAP26-12850-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-UBE2D2/ARHGAP26-12850-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-UBE2D2/ARHGAP26-12850-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-UBE2D2/ARHGAP26-12850-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-UBE2D2/ARHGAP26-12850-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-UBE2D2/ARHGAP26-12850-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-UBE2D2/ARHGAP26-12850-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-UBE2D2/ARHGAP26-12850-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-UBE2D2/ARHGAP26-12850-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-UBE2D2/ARHGAP26-12850-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-UBE2D2/ARHGAP26-12850-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-UBE2D2/ARHGAP26-12850-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-UBE2D2/ARHGAP26-12850-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-UBE2D2/ARHGAP26-12850-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-UBE2D2/ARHGAP26-12850-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-UBE2D2/ARHGAP26-12850-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-UBE2D2/ARHGAP26-12850-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-UBE2D2/ARHGAP26-12850-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-UBE2D2/ARHGAP26-12850-AQAQ |
467nm;467nm |
418nm;418nm |
|
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