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TXNRD1-HCFC2 Gene Fusion FISH Probe

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Catalog: GFFP-TXNRD1/HCFC2-12558
Classification: Gene Fusion FISH Probes
Description: The TXNRD1-HCFC2 Gene Fusion FISH Probecan detect the fusion of TXNRD1 and HCFC2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: TXNRD1-HCFC2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Thioredoxin Reductase 1
Gene Summary 1 The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes an ubiquitously expressed, cytosolic form of TrxR, which functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing, primarily at the 5' end, results in transcript variants encoding same or different isoforms, including a glutaredoxin-containing isoform that is predominantly expressed in testis. [provided by RefSeq, May 2017]
Chromosome 1 Chromosome 12
Locus 1 12q23.3
Coordinates 1 This gene maps to 104609558-104744062 in GRCh37 coordinates.
Gene Name 2 Host Cell Factor C2
Gene Summary 2 This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome12
Locus 2 12q23.3
Coordinates 2 This gene maps to 104458235-104500304 in GRCh37 coordinates.
Associated Diseases Lung Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-TXNRD1/HCFC2-12558-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-TXNRD1/HCFC2-12558-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-TXNRD1/HCFC2-12558-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-TXNRD1/HCFC2-12558-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-TXNRD1/HCFC2-12558-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-TXNRD1/HCFC2-12558-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-TXNRD1/HCFC2-12558-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-TXNRD1/HCFC2-12558-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-TXNRD1/HCFC2-12558-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-TXNRD1/HCFC2-12558-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-TXNRD1/HCFC2-12558-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-TXNRD1/HCFC2-12558-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-TXNRD1/HCFC2-12558-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-TXNRD1/HCFC2-12558-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-TXNRD1/HCFC2-12558-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-TXNRD1/HCFC2-12558-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-TXNRD1/HCFC2-12558-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-TXNRD1/HCFC2-12558-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-TXNRD1/HCFC2-12558-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-TXNRD1/HCFC2-12558-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-TXNRD1/HCFC2-12558-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-TXNRD1/HCFC2-12558-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-TXNRD1/HCFC2-12558-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-TXNRD1/HCFC2-12558-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-TXNRD1/HCFC2-12558-AQAQ 467nm;467nm 418nm;418nm

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