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TRIM24-BRAF Gene Fusion FISH Probe

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Catalog: GFFP-TRIM24/BRAF-15690
Classification: Gene Fusion FISH Probes
Description: The TRIM24-BRAF Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: TRIM24-BRAF Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 B-Raf Proto-oncogene, Serine/threonine Kinase
Gene Summary 1 This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017]
Chromosome 1 Chromosome 7
Locus 1 7q34
Coordinates 1 This gene maps to 140433812-140624564in GRCh37 coordinates.
Gene Name 2 Tripartite Motif Containing 24
Gene Summary 2 The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome7
Locus 2 7q33-q34
Coordinates 2 This gene maps to 138145078-138270332 in GRCh37 coordinates.
Associated Diseases Liver Hepatocellular Carcinoma; Rectum Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-TRIM24/BRAF-15690-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-TRIM24/BRAF-15690-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-TRIM24/BRAF-15690-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-TRIM24/BRAF-15690-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-TRIM24/BRAF-15690-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-TRIM24/BRAF-15690-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-TRIM24/BRAF-15690-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-TRIM24/BRAF-15690-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-TRIM24/BRAF-15690-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-TRIM24/BRAF-15690-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-TRIM24/BRAF-15690-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-TRIM24/BRAF-15690-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-TRIM24/BRAF-15690-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-TRIM24/BRAF-15690-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-TRIM24/BRAF-15690-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-TRIM24/BRAF-15690-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-TRIM24/BRAF-15690-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-TRIM24/BRAF-15690-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-TRIM24/BRAF-15690-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-TRIM24/BRAF-15690-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-TRIM24/BRAF-15690-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-TRIM24/BRAF-15690-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-TRIM24/BRAF-15690-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-TRIM24/BRAF-15690-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-TRIM24/BRAF-15690-AQAQ 467nm;467nm 418nm;418nm

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