TPM3-NTRK1 Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-TPM3/NTRK1-15697 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The TPM3-NTRK1 Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
TPM3-NTRK1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Neurotrophic Receptor Tyrosine Kinase 1 |
Gene Summary 1 |
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 1 |
Locus 1 |
1q23.1 |
Coordinates 1 |
This gene maps to 156785541-156851642in GRCh37 coordinates. |
Gene Name 2 |
Tropomyosin 3 |
Gene Summary 2 |
This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] |
Chromosome 2 |
Chromosome1 |
Locus 2 |
1q21.3 |
Coordinates 2 |
This gene maps to 154134289-154164609 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma; Thyroid Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-TPM3/NTRK1-15697-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-TPM3/NTRK1-15697-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-TPM3/NTRK1-15697-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-TPM3/NTRK1-15697-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-TPM3/NTRK1-15697-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-TPM3/NTRK1-15697-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-TPM3/NTRK1-15697-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-TPM3/NTRK1-15697-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-TPM3/NTRK1-15697-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-TPM3/NTRK1-15697-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-TPM3/NTRK1-15697-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-TPM3/NTRK1-15697-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-TPM3/NTRK1-15697-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-TPM3/NTRK1-15697-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-TPM3/NTRK1-15697-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-TPM3/NTRK1-15697-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-TPM3/NTRK1-15697-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-TPM3/NTRK1-15697-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-TPM3/NTRK1-15697-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-TPM3/NTRK1-15697-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-TPM3/NTRK1-15697-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-TPM3/NTRK1-15697-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-TPM3/NTRK1-15697-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-TPM3/NTRK1-15697-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-TPM3/NTRK1-15697-AQAQ |
467nm;467nm |
418nm;418nm |
|
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