TMPRSS2-INPP4B Gene Fusion FISH Probe
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Catalog: |
GFFP-TMPRSS2/INPP4B-12358 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The TMPRSS2-INPP4B Gene Fusion FISH Probecan detect the fusion of TMPRSS2 and INPP4B genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
TMPRSS2-INPP4B Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Transmembrane Protease, Serine 2 |
Gene Summary 1 |
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] |
Chromosome 1 |
Chromosome 21 |
Locus 1 |
21q22.3 |
Coordinates 1 |
This gene maps to 42836477-42880085 in GRCh37 coordinates. |
Gene Name 2 |
Inositol Polyphosphate-4-phosphatase Type II B |
Gene Summary 2 |
INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome4 |
Locus 2 |
4q31.21 |
Coordinates 2 |
This gene maps to 142949181-143767604 in GRCh37 coordinates. |
Associated Diseases |
Prostate Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-TMPRSS2/INPP4B-12358-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-TMPRSS2/INPP4B-12358-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-TMPRSS2/INPP4B-12358-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-TMPRSS2/INPP4B-12358-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-TMPRSS2/INPP4B-12358-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-TMPRSS2/INPP4B-12358-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-TMPRSS2/INPP4B-12358-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-TMPRSS2/INPP4B-12358-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-TMPRSS2/INPP4B-12358-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-TMPRSS2/INPP4B-12358-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-TMPRSS2/INPP4B-12358-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-TMPRSS2/INPP4B-12358-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-TMPRSS2/INPP4B-12358-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-TMPRSS2/INPP4B-12358-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-TMPRSS2/INPP4B-12358-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-TMPRSS2/INPP4B-12358-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-TMPRSS2/INPP4B-12358-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-TMPRSS2/INPP4B-12358-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-TMPRSS2/INPP4B-12358-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-TMPRSS2/INPP4B-12358-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-TMPRSS2/INPP4B-12358-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-TMPRSS2/INPP4B-12358-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-TMPRSS2/INPP4B-12358-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-TMPRSS2/INPP4B-12358-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-TMPRSS2/INPP4B-12358-AQAQ |
467nm;467nm |
418nm;418nm |
|
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