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TMEM123-MMP20 Gene Fusion FISH Probe

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Catalog: GFFP-TMEM123/MMP20-15665
Classification: Gene Fusion FISH Probes
Description: The TMEM123-MMP20 Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: TMEM123-MMP20 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Matrix Metallopeptidase 20
Gene Summary 1 Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3. [provided by RefSeq, Aug 2011]
Chromosome 1 Chromosome 11
Locus 1 11q22.2
Coordinates 1 This gene maps to 102447565-102496063in GRCh37 coordinates.
Gene Name 2 Transmembrane Protein 123
Gene Summary 2 This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome11
Locus 2 11q22.2
Coordinates 2 This gene maps to 102267055-102323775 in GRCh37 coordinates.
Associated Diseases Lung Adenocarcinoma; Colon Adenocarcinoma; Stomach Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-TMEM123/MMP20-15665-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-TMEM123/MMP20-15665-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-TMEM123/MMP20-15665-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-TMEM123/MMP20-15665-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-TMEM123/MMP20-15665-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-TMEM123/MMP20-15665-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-TMEM123/MMP20-15665-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-TMEM123/MMP20-15665-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-TMEM123/MMP20-15665-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-TMEM123/MMP20-15665-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-TMEM123/MMP20-15665-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-TMEM123/MMP20-15665-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-TMEM123/MMP20-15665-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-TMEM123/MMP20-15665-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-TMEM123/MMP20-15665-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-TMEM123/MMP20-15665-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-TMEM123/MMP20-15665-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-TMEM123/MMP20-15665-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-TMEM123/MMP20-15665-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-TMEM123/MMP20-15665-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-TMEM123/MMP20-15665-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-TMEM123/MMP20-15665-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-TMEM123/MMP20-15665-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-TMEM123/MMP20-15665-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-TMEM123/MMP20-15665-AQAQ 467nm;467nm 418nm;418nm

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