TMEM123-MMP10 Gene Fusion FISH Probe
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Catalog: |
GFFP-TMEM123/MMP10-12123 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The TMEM123-MMP10 Gene Fusion FISH Probecan detect the fusion of TMEM123 and MMP10 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
TMEM123-MMP10 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Matrix Metallopeptidase 10 |
Gene Summary 1 |
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11q22.2 |
Coordinates 1 |
This gene maps to 102641232-102651359 in GRCh37 coordinates. |
Gene Name 2 |
Transmembrane Protein 123 |
Gene Summary 2 |
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11q22.2 |
Coordinates 2 |
This gene maps to 102267055-102323775 in GRCh37 coordinates. |
Associated Diseases |
Uterine Corpus Endometrial Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-TMEM123/MMP10-12123-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-TMEM123/MMP10-12123-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-TMEM123/MMP10-12123-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-TMEM123/MMP10-12123-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-TMEM123/MMP10-12123-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-TMEM123/MMP10-12123-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-TMEM123/MMP10-12123-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-TMEM123/MMP10-12123-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-TMEM123/MMP10-12123-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-TMEM123/MMP10-12123-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-TMEM123/MMP10-12123-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-TMEM123/MMP10-12123-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-TMEM123/MMP10-12123-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-TMEM123/MMP10-12123-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-TMEM123/MMP10-12123-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-TMEM123/MMP10-12123-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-TMEM123/MMP10-12123-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-TMEM123/MMP10-12123-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-TMEM123/MMP10-12123-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-TMEM123/MMP10-12123-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-TMEM123/MMP10-12123-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-TMEM123/MMP10-12123-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-TMEM123/MMP10-12123-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-TMEM123/MMP10-12123-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-TMEM123/MMP10-12123-AQAQ |
467nm;467nm |
418nm;418nm |
|
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