banner
  • Home
  • TIAM1-FBLIM1 Gene Fusion FISH Probe

TIAM1-FBLIM1 Gene Fusion FISH Probe

Add to Cart
Catalog: GFFP-TIAM1/FBLIM1-12199
Classification: Gene Fusion FISH Probes
Description: The TIAM1-FBLIM1 Gene Fusion FISH Probecan detect the fusion of TIAM1 and FBLIM1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: TIAM1-FBLIM1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 T-cell Lymphoma Invasion And Metastasis 1
Gene Summary 1 This gene encodes a RAC1-specific guanine nucleotide exchange factor (GEF). GEFs mediate the exchange of guanosine diphosphate (GDP) for guanosine triphosphate (GTP). The binding of GTP induces a conformational change in RAC1 that allows downstream effectors to bind and transduce a signal. This gene thus regulates RAC1 signaling pathways that affect cell shape, migration, adhesion, growth, survival, and polarity, as well as influencing actin cytoskeletal formation, endocytosis, and membrane trafficking. This gene thus plays an important role in cell invasion, metastasis, and carcinogenesis. In addition to RAC1, the encoded protein activates additional Rho-like GTPases such as CDC42, RAC2, RAC3 and RHOA. This gene encodes multiple protein isoforms that experience a diverse array of intramolecular, protein-protein, and phosphorylation interactions as well as phosphoinositide binding. Both the longer and shorter isoforms have C-terminal Dbl homology (DH) and pleckstrin homology (PH) domains while only the longer isoforms of this gene have the N-terminal myristoylation site and the downstream N-terminal PH domain, ras-binding domain (RBD), and PSD-95/DlgA/ZO-1 (PDZ) domain. [provided by RefSeq, Jul 2017]
Chromosome 1 Chromosome 21
Locus 1 21q22.11
Coordinates 1 This gene maps to 32490735-32931290 in GRCh37 coordinates.
Gene Name 2 Filamin Binding LIM Protein 1
Gene Summary 2 This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome1
Locus 2 1p36.21
Coordinates 2 This gene maps to 16085254-16113084 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-TIAM1/FBLIM1-12199-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-TIAM1/FBLIM1-12199-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-TIAM1/FBLIM1-12199-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-TIAM1/FBLIM1-12199-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-TIAM1/FBLIM1-12199-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-TIAM1/FBLIM1-12199-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-TIAM1/FBLIM1-12199-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-TIAM1/FBLIM1-12199-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-TIAM1/FBLIM1-12199-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-TIAM1/FBLIM1-12199-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-TIAM1/FBLIM1-12199-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-TIAM1/FBLIM1-12199-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-TIAM1/FBLIM1-12199-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-TIAM1/FBLIM1-12199-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-TIAM1/FBLIM1-12199-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-TIAM1/FBLIM1-12199-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-TIAM1/FBLIM1-12199-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-TIAM1/FBLIM1-12199-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-TIAM1/FBLIM1-12199-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-TIAM1/FBLIM1-12199-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-TIAM1/FBLIM1-12199-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-TIAM1/FBLIM1-12199-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-TIAM1/FBLIM1-12199-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-TIAM1/FBLIM1-12199-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-TIAM1/FBLIM1-12199-AQAQ 467nm;467nm 418nm;418nm

Other Products

Online Inquiry

Order

0
Inquiry Basket ( 0 ) Choose Dye*