TFIP11-IL17RA Gene Fusion FISH Probe
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Catalog: |
GFFP-TFIP11/IL17RA-11924 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The TFIP11-IL17RA Gene Fusion FISH Probecan detect the fusion of TFIP11 and IL17RA genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
TFIP11-IL17RA Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Interleukin 17 Receptor A |
Gene Summary 1 |
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014] |
Chromosome 1 |
Chromosome 22 |
Locus 1 |
22q11.1 |
Coordinates 1 |
This gene maps to 17565850-17596584 in GRCh37 coordinates. |
Gene Name 2 |
Tuftelin Interacting Protein 11 |
Gene Summary 2 |
This gene encodes a protein component of the spliceosome that promotes the release of the lariat-intron during late-stage splicing through the recruitment of a pre-mRNA splicing factor called DEAH-box helicase 15. The encoded protein contains a G-patch domain, a hallmark of RNA-processing proteins, that binds DEAH-box helicase 15. This protein contains an atypical nuclear localization sequence as well as a nuclear speckle-targeting sequence, enabling it to localize to distinct speckled regions within the cell nucleus. Polymorphisms in this gene are associated with dental caries suggesting a role in amelogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016] |
Chromosome 2 |
Chromosome22 |
Locus 2 |
22q12.1 |
Coordinates 2 |
This gene maps to 26887893-26908437 in GRCh37 coordinates. |
Associated Diseases |
Bladder Urothelial Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-TFIP11/IL17RA-11924-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-TFIP11/IL17RA-11924-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-TFIP11/IL17RA-11924-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-TFIP11/IL17RA-11924-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-TFIP11/IL17RA-11924-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-TFIP11/IL17RA-11924-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-TFIP11/IL17RA-11924-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-TFIP11/IL17RA-11924-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-TFIP11/IL17RA-11924-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-TFIP11/IL17RA-11924-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-TFIP11/IL17RA-11924-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-TFIP11/IL17RA-11924-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-TFIP11/IL17RA-11924-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-TFIP11/IL17RA-11924-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-TFIP11/IL17RA-11924-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-TFIP11/IL17RA-11924-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-TFIP11/IL17RA-11924-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-TFIP11/IL17RA-11924-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-TFIP11/IL17RA-11924-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-TFIP11/IL17RA-11924-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-TFIP11/IL17RA-11924-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-TFIP11/IL17RA-11924-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-TFIP11/IL17RA-11924-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-TFIP11/IL17RA-11924-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-TFIP11/IL17RA-11924-AQAQ |
467nm;467nm |
418nm;418nm |
|
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