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TFE3-PRCC Gene Fusion FISH Probe

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Catalog: GFFP-TFE3/PRCC-15653
Classification: Gene Fusion FISH Probes
Description: The TFE3-PRCC Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: TFE3-PRCC Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Papillary Renal Cell Carcinoma (translocation-associated)
Gene Summary 1 This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010]
Chromosome 1 Chromosome 1
Locus 1 1q23.1
Coordinates 1 This gene maps to 156737273-156770609in GRCh37 coordinates.
Gene Name 2 Transcription Factor Binding To IGHM Enhancer 3
Gene Summary 2 This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Chromosome 2 ChromosomeX
Locus 2 Xp11.23
Coordinates 2 This gene maps to 48886241-48900990 in GRCh37 coordinates.
Associated Diseases Kidney Renal Papillary Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-TFE3/PRCC-15653-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-TFE3/PRCC-15653-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-TFE3/PRCC-15653-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-TFE3/PRCC-15653-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-TFE3/PRCC-15653-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-TFE3/PRCC-15653-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-TFE3/PRCC-15653-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-TFE3/PRCC-15653-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-TFE3/PRCC-15653-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-TFE3/PRCC-15653-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-TFE3/PRCC-15653-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-TFE3/PRCC-15653-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-TFE3/PRCC-15653-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-TFE3/PRCC-15653-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-TFE3/PRCC-15653-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-TFE3/PRCC-15653-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-TFE3/PRCC-15653-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-TFE3/PRCC-15653-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-TFE3/PRCC-15653-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-TFE3/PRCC-15653-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-TFE3/PRCC-15653-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-TFE3/PRCC-15653-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-TFE3/PRCC-15653-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-TFE3/PRCC-15653-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-TFE3/PRCC-15653-AQAQ 467nm;467nm 418nm;418nm

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