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| Catalog: | GFFP-TECR/PKN1-15656 |
| Classification: | Gene Fusion FISH Probes |
| Description: | The TECR-PKN1 Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Application: | TECR-PKN1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | 7-10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name 1 | Protein Kinase N1 |
| Gene Summary 1 | The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
| Chromosome 1 | Chromosome 19 |
| Locus 1 | 19p13.12 |
| Coordinates 1 | This gene maps to 14544165-14582679in GRCh37 coordinates. |
| Gene Name 2 | Trans-2,3-enoyl-CoA Reductase |
| Gene Summary 2 | This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2011] |
| Chromosome 2 | Chromosome19 |
| Locus 2 | 19p13.12 |
| Coordinates 2 | This gene maps to 14640378-14676792 in GRCh37 coordinates. |
| Associated Diseases | Lung Squamous Cell Carcinoma; Uterine Corpus Endometrial Carcinoma |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | RE; RE | GFFP-TECR/PKN1-15656-RERE | 599nm;599nm | 580nm;580nm | |
| 2 | RE; OR | GFFP-TECR/PKN1-15656-REOR | 599nm;573nm | 580nm;548nm | |
| 3 | RE; GO | GFFP-TECR/PKN1-15656-REGO | 599nm;551nm | 580nm;525nm | |
| 4 | RE; GR | GFFP-TECR/PKN1-15656-REGR | 599nm;515nm | 580nm;491nm | |
| 5 | RE; AQ | GFFP-TECR/PKN1-15656-REAQ | 599nm;467nm | 580nm;418nm | |
| 6 | OR; RE | GFFP-TECR/PKN1-15656-ORRE | 573nm;599nm | 548nm;580nm | |
| 7 | OR; OR | GFFP-TECR/PKN1-15656-OROR | 573nm;573nm | 548nm;548nm | |
| 8 | OR; GO | GFFP-TECR/PKN1-15656-ORGO | 573nm;551nm | 548nm;525nm | |
| 9 | OR; GR | GFFP-TECR/PKN1-15656-ORGR | 573nm;515nm | 548nm;491nm | |
| 10 | OR; AQ | GFFP-TECR/PKN1-15656-ORAQ | 573nm;467nm | 548nm;418nm | |
| 11 | GO; RE | GFFP-TECR/PKN1-15656-GORE | 551nm;599nm | 525nm;580nm | |
| 12 | GO; OR | GFFP-TECR/PKN1-15656-GOOR | 551nm;573nm | 525nm;548nm | |
| 13 | GO; GO | GFFP-TECR/PKN1-15656-GOGO | 551nm;551nm | 525nm;525nm | |
| 14 | GO; GR | GFFP-TECR/PKN1-15656-GOGR | 551nm;515nm | 525nm;491nm | |
| 15 | GO; AQ | GFFP-TECR/PKN1-15656-GOAQ | 551nm;467nm | 525nm;418nm | |
| 16 | GR; RE | GFFP-TECR/PKN1-15656-GRRE | 515nm;599nm | 491nm;580nm | |
| 17 | GR; OR | GFFP-TECR/PKN1-15656-GROR | 515nm;573nm | 491nm;548nm | |
| 18 | GR; GO | GFFP-TECR/PKN1-15656-GRGO | 515nm;551nm | 491nm;525nm | |
| 19 | GR; GR | GFFP-TECR/PKN1-15656-GRGR | 515nm;515nm | 491nm;491nm | |
| 20 | GR; AQ | GFFP-TECR/PKN1-15656-GRAQ | 515nm;467nm | 491nm;418nm | |
| 21 | AQ; RE | GFFP-TECR/PKN1-15656-AQRE | 467nm;599nm | 418nm;580nm | |
| 22 | AQ; OR | GFFP-TECR/PKN1-15656-AQOR | 467nm;573nm | 418nm;548nm | |
| 23 | AQ; GO | GFFP-TECR/PKN1-15656-AQGO | 467nm;551nm | 418nm;525nm | |
| 24 | AQ; GR | GFFP-TECR/PKN1-15656-AQGR | 467nm;515nm | 418nm;491nm | |
| 25 | AQ; AQ | GFFP-TECR/PKN1-15656-AQAQ | 467nm;467nm | 418nm;418nm |
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