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TBP-FAM120B Gene Fusion FISH Probe

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Catalog: GFFP-TBP/FAM120B-14654
Classification: Gene Fusion FISH Probes
Description: The TBP-FAM120B Gene Fusion FISH Probecan detect the fusion of TBP and FAM120B genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: TBP-FAM120B Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 TATA-box Binding Protein
Gene Summary 1 Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 25-42, and expansion of the number of repeats to 45-66 increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016]
Chromosome 1 Chromosome 6
Locus 1 6q27
Coordinates 1 This gene maps to 170863420-170881958 in GRCh37 coordinates.
Gene Name 2 Family With Sequence Similarity 120B
Gene Summary 2 The Family With Sequence Similarity 120B (FAM120B) gene is located on chr6 :170615843-170714237 at 6q27.
Chromosome 2 Chromosome6
Locus 2 6q27
Coordinates 2 This gene maps to 170615843-170714237 in GRCh37 coordinates.
Associated Diseases Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-TBP/FAM120B-14654-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-TBP/FAM120B-14654-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-TBP/FAM120B-14654-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-TBP/FAM120B-14654-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-TBP/FAM120B-14654-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-TBP/FAM120B-14654-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-TBP/FAM120B-14654-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-TBP/FAM120B-14654-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-TBP/FAM120B-14654-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-TBP/FAM120B-14654-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-TBP/FAM120B-14654-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-TBP/FAM120B-14654-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-TBP/FAM120B-14654-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-TBP/FAM120B-14654-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-TBP/FAM120B-14654-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-TBP/FAM120B-14654-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-TBP/FAM120B-14654-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-TBP/FAM120B-14654-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-TBP/FAM120B-14654-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-TBP/FAM120B-14654-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-TBP/FAM120B-14654-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-TBP/FAM120B-14654-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-TBP/FAM120B-14654-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-TBP/FAM120B-14654-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-TBP/FAM120B-14654-AQAQ 467nm;467nm 418nm;418nm

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