TAF3-SVIL Gene Fusion FISH Probe
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Catalog: |
GFFP-TAF3/SVIL-11848 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The TAF3-SVIL Gene Fusion FISH Probecan detect the fusion of TAF3 and SVIL genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
TAF3-SVIL Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Supervillin |
Gene Summary 1 |
This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Several transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Apr 2016] |
Chromosome 1 |
Chromosome 10 |
Locus 1 |
10p11.23 |
Coordinates 1 |
This gene maps to 29746276-30024730 in GRCh37 coordinates. |
Gene Name 2 |
TATA-box Binding Protein Associated Factor 3 |
Gene Summary 2 |
The highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA box-binding protein (TBP; MIM 600075) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors (Gangloff et al., 2001 [PubMed 11438666]).[supplied by OMIM, May 2009] |
Chromosome 2 |
Chromosome10 |
Locus 2 |
10p14 |
Coordinates 2 |
This gene maps to 7860672-8056714 in GRCh37 coordinates. |
Associated Diseases |
Skin Cutaneous Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-TAF3/SVIL-11848-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-TAF3/SVIL-11848-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-TAF3/SVIL-11848-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-TAF3/SVIL-11848-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-TAF3/SVIL-11848-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-TAF3/SVIL-11848-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-TAF3/SVIL-11848-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-TAF3/SVIL-11848-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-TAF3/SVIL-11848-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-TAF3/SVIL-11848-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-TAF3/SVIL-11848-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-TAF3/SVIL-11848-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-TAF3/SVIL-11848-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-TAF3/SVIL-11848-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-TAF3/SVIL-11848-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-TAF3/SVIL-11848-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-TAF3/SVIL-11848-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-TAF3/SVIL-11848-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-TAF3/SVIL-11848-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-TAF3/SVIL-11848-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-TAF3/SVIL-11848-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-TAF3/SVIL-11848-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-TAF3/SVIL-11848-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-TAF3/SVIL-11848-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-TAF3/SVIL-11848-AQAQ |
467nm;467nm |
418nm;418nm |
|
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