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SYK-AUH Gene Fusion FISH Probe

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Catalog: GFFP-SYK/AUH-11617
Classification: Gene Fusion FISH Probes
Description: The SYK-AUH Gene Fusion FISH Probecan detect the fusion of SYK and AUH genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SYK-AUH Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 AU RNA Binding Methylglutaconyl-CoA Hydratase
Gene Summary 1 This gene encodes bifunctional mitochondrial protein that has both RNA-binding and hydratase activities. The encoded protein is a methylglutaconyl-CoA hydratase that catalyzes the hydration of 3-methylglutaconyl-CoA to 3-hydroxy-3-methyl-glutaryl-CoA, a critical step in the leucine degradation pathway. This protein also binds AU-rich elements (AREs) found in the 3' UTRs of rapidly decaying mRNAs including c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. This protein is localizes to the mitochondrial matrix and the inner mitochondrial membrane and may be involved in mitochondrial protein synthesis. Mutations in this gene are the cause of 3-methylglutaconic aciduria, type I. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Chromosome 1 Chromosome 9
Locus 1 9q22.31
Coordinates 1 This gene maps to 93976096-94124206 in GRCh37 coordinates.
Gene Name 2 Spleen Associated Tyrosine Kinase
Gene Summary 2 This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Chromosome 2 Chromosome9
Locus 2 9q22.2
Coordinates 2 This gene maps to 93564011-93660842 in GRCh37 coordinates.
Associated Diseases Liver Hepatocellular Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SYK/AUH-11617-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SYK/AUH-11617-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SYK/AUH-11617-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SYK/AUH-11617-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SYK/AUH-11617-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SYK/AUH-11617-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SYK/AUH-11617-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SYK/AUH-11617-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SYK/AUH-11617-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SYK/AUH-11617-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SYK/AUH-11617-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SYK/AUH-11617-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SYK/AUH-11617-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SYK/AUH-11617-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SYK/AUH-11617-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SYK/AUH-11617-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SYK/AUH-11617-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SYK/AUH-11617-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SYK/AUH-11617-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SYK/AUH-11617-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SYK/AUH-11617-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SYK/AUH-11617-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SYK/AUH-11617-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SYK/AUH-11617-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SYK/AUH-11617-AQAQ 467nm;467nm 418nm;418nm

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