SYK-AUH Gene Fusion FISH Probe
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Catalog: |
GFFP-SYK/AUH-11617 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SYK-AUH Gene Fusion FISH Probecan detect the fusion of SYK and AUH genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SYK-AUH Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
AU RNA Binding Methylglutaconyl-CoA Hydratase |
Gene Summary 1 |
This gene encodes bifunctional mitochondrial protein that has both RNA-binding and hydratase activities. The encoded protein is a methylglutaconyl-CoA hydratase that catalyzes the hydration of 3-methylglutaconyl-CoA to 3-hydroxy-3-methyl-glutaryl-CoA, a critical step in the leucine degradation pathway. This protein also binds AU-rich elements (AREs) found in the 3' UTRs of rapidly decaying mRNAs including c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. This protein is localizes to the mitochondrial matrix and the inner mitochondrial membrane and may be involved in mitochondrial protein synthesis. Mutations in this gene are the cause of 3-methylglutaconic aciduria, type I. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
Chromosome 1 |
Chromosome 9 |
Locus 1 |
9q22.31 |
Coordinates 1 |
This gene maps to 93976096-94124206 in GRCh37 coordinates. |
Gene Name 2 |
Spleen Associated Tyrosine Kinase |
Gene Summary 2 |
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] |
Chromosome 2 |
Chromosome9 |
Locus 2 |
9q22.2 |
Coordinates 2 |
This gene maps to 93564011-93660842 in GRCh37 coordinates. |
Associated Diseases |
Liver Hepatocellular Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SYK/AUH-11617-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SYK/AUH-11617-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SYK/AUH-11617-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SYK/AUH-11617-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SYK/AUH-11617-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SYK/AUH-11617-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SYK/AUH-11617-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SYK/AUH-11617-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SYK/AUH-11617-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SYK/AUH-11617-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SYK/AUH-11617-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SYK/AUH-11617-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SYK/AUH-11617-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SYK/AUH-11617-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SYK/AUH-11617-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SYK/AUH-11617-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SYK/AUH-11617-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SYK/AUH-11617-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SYK/AUH-11617-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SYK/AUH-11617-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SYK/AUH-11617-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SYK/AUH-11617-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SYK/AUH-11617-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SYK/AUH-11617-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SYK/AUH-11617-AQAQ |
467nm;467nm |
418nm;418nm |
|
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