SULF2-WFDC3 Gene Fusion FISH Probe
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Catalog: |
GFFP-SULF2/WFDC3-11648 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SULF2-WFDC3 Gene Fusion FISH Probecan detect the fusion of SULF2 and WFDC3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SULF2-WFDC3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Sulfatase 2 |
Gene Summary 1 |
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008] |
Chromosome 1 |
Chromosome 20 |
Locus 1 |
20q13.12 |
Coordinates 1 |
This gene maps to 46286149-46415360 in GRCh37 coordinates. |
Gene Name 2 |
WAP Four-disulfide Core Domain 3 |
Gene Summary 2 |
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains four WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Alternatively spliced transcript variants have been observed but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome20 |
Locus 2 |
20q13.12 |
Coordinates 2 |
This gene maps to 44402846-44420547 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SULF2/WFDC3-11648-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SULF2/WFDC3-11648-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SULF2/WFDC3-11648-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SULF2/WFDC3-11648-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SULF2/WFDC3-11648-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SULF2/WFDC3-11648-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SULF2/WFDC3-11648-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SULF2/WFDC3-11648-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SULF2/WFDC3-11648-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SULF2/WFDC3-11648-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SULF2/WFDC3-11648-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SULF2/WFDC3-11648-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SULF2/WFDC3-11648-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SULF2/WFDC3-11648-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SULF2/WFDC3-11648-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SULF2/WFDC3-11648-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SULF2/WFDC3-11648-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SULF2/WFDC3-11648-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SULF2/WFDC3-11648-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SULF2/WFDC3-11648-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SULF2/WFDC3-11648-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SULF2/WFDC3-11648-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SULF2/WFDC3-11648-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SULF2/WFDC3-11648-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SULF2/WFDC3-11648-AQAQ |
467nm;467nm |
418nm;418nm |
|
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