STXBP5-SASH1 Gene Fusion FISH Probe
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Catalog: |
GFFP-STXBP5/SASH1-11665 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The STXBP5-SASH1 Gene Fusion FISH Probecan detect the fusion of STXBP5 and SASH1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
STXBP5-SASH1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
SAM And SH3 Domain Containing 1 |
Gene Summary 1 |
This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients. [provided by RefSeq, Oct 2016] |
Chromosome 1 |
Chromosome 6 |
Locus 1 |
6q24.3-q25.1 |
Coordinates 1 |
This gene maps to 148663728-148873184 in GRCh37 coordinates. |
Gene Name 2 |
Syntaxin Binding Protein 5 |
Gene Summary 2 |
Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome6 |
Locus 2 |
6q24.3 |
Coordinates 2 |
This gene maps to 147525493-147711612 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-STXBP5/SASH1-11665-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-STXBP5/SASH1-11665-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-STXBP5/SASH1-11665-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-STXBP5/SASH1-11665-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-STXBP5/SASH1-11665-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-STXBP5/SASH1-11665-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-STXBP5/SASH1-11665-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-STXBP5/SASH1-11665-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-STXBP5/SASH1-11665-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-STXBP5/SASH1-11665-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-STXBP5/SASH1-11665-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-STXBP5/SASH1-11665-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-STXBP5/SASH1-11665-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-STXBP5/SASH1-11665-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-STXBP5/SASH1-11665-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-STXBP5/SASH1-11665-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-STXBP5/SASH1-11665-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-STXBP5/SASH1-11665-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-STXBP5/SASH1-11665-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-STXBP5/SASH1-11665-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-STXBP5/SASH1-11665-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-STXBP5/SASH1-11665-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-STXBP5/SASH1-11665-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-STXBP5/SASH1-11665-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-STXBP5/SASH1-11665-AQAQ |
467nm;467nm |
418nm;418nm |
|
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