STC2-TYK2 Gene Fusion FISH Probe
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Catalog: |
GFFP-STC2/TYK2-11382 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The STC2-TYK2 Gene Fusion FISH Probecan detect the fusion of STC2 and TYK2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
STC2-TYK2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Tyrosine Kinase 2 |
Gene Summary 1 |
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 19 |
Locus 1 |
19p13.2 |
Coordinates 1 |
This gene maps to 10461203-10491248 in GRCh37 coordinates. |
Gene Name 2 |
Stanniocalcin 2 |
Gene Summary 2 |
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome5 |
Locus 2 |
5q35.2 |
Coordinates 2 |
This gene maps to 172741725-172756506 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-STC2/TYK2-11382-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-STC2/TYK2-11382-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-STC2/TYK2-11382-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-STC2/TYK2-11382-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-STC2/TYK2-11382-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-STC2/TYK2-11382-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-STC2/TYK2-11382-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-STC2/TYK2-11382-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-STC2/TYK2-11382-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-STC2/TYK2-11382-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-STC2/TYK2-11382-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-STC2/TYK2-11382-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-STC2/TYK2-11382-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-STC2/TYK2-11382-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-STC2/TYK2-11382-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-STC2/TYK2-11382-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-STC2/TYK2-11382-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-STC2/TYK2-11382-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-STC2/TYK2-11382-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-STC2/TYK2-11382-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-STC2/TYK2-11382-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-STC2/TYK2-11382-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-STC2/TYK2-11382-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-STC2/TYK2-11382-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-STC2/TYK2-11382-AQAQ |
467nm;467nm |
418nm;418nm |
|
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