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STAU1-MRPL4 Gene Fusion FISH Probe

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Catalog: GFFP-STAU1/MRPL4-11388
Classification: Gene Fusion FISH Probes
Description: The STAU1-MRPL4 Gene Fusion FISH Probecan detect the fusion of STAU1 and MRPL4 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: STAU1-MRPL4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Staufen Double-stranded RNA Binding Protein 1
Gene Summary 1 Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 20
Locus 1 20q13.13
Coordinates 1 This gene maps to 47729875-47804904 in GRCh37 coordinates.
Gene Name 2 Mitochondrial Ribosomal Protein L4
Gene Summary 2 Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified alternatively spliced variants that encode different protein isoforms. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome19
Locus 2 19p13.2
Coordinates 2 This gene maps to 10362639-10370736 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-STAU1/MRPL4-11388-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-STAU1/MRPL4-11388-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-STAU1/MRPL4-11388-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-STAU1/MRPL4-11388-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-STAU1/MRPL4-11388-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-STAU1/MRPL4-11388-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-STAU1/MRPL4-11388-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-STAU1/MRPL4-11388-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-STAU1/MRPL4-11388-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-STAU1/MRPL4-11388-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-STAU1/MRPL4-11388-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-STAU1/MRPL4-11388-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-STAU1/MRPL4-11388-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-STAU1/MRPL4-11388-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-STAU1/MRPL4-11388-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-STAU1/MRPL4-11388-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-STAU1/MRPL4-11388-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-STAU1/MRPL4-11388-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-STAU1/MRPL4-11388-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-STAU1/MRPL4-11388-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-STAU1/MRPL4-11388-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-STAU1/MRPL4-11388-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-STAU1/MRPL4-11388-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-STAU1/MRPL4-11388-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-STAU1/MRPL4-11388-AQAQ 467nm;467nm 418nm;418nm

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