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STAT5A-ARNTL2 Gene Fusion FISH Probe

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Catalog: GFFP-STAT5A/ARNTL2-11394
Classification: Gene Fusion FISH Probes
Description: The STAT5A-ARNTL2 Gene Fusion FISH Probecan detect the fusion of STAT5A and ARNTL2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: STAT5A-ARNTL2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Signal Transducer And Activator Of Transcription 5A
Gene Summary 1 The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
Chromosome 1 Chromosome 17
Locus 1 17q21.2
Coordinates 1 This gene maps to 40439564-40463960 in GRCh37 coordinates.
Gene Name 2 Aryl Hydrocarbon Receptor Nuclear Translocator Like 2
Gene Summary 2 This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Chromosome 2 Chromosome12
Locus 2 12p11.23
Coordinates 2 This gene maps to 27485987-27573466 in GRCh37 coordinates.
Associated Diseases Lung Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-STAT5A/ARNTL2-11394-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-STAT5A/ARNTL2-11394-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-STAT5A/ARNTL2-11394-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-STAT5A/ARNTL2-11394-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-STAT5A/ARNTL2-11394-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-STAT5A/ARNTL2-11394-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-STAT5A/ARNTL2-11394-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-STAT5A/ARNTL2-11394-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-STAT5A/ARNTL2-11394-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-STAT5A/ARNTL2-11394-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-STAT5A/ARNTL2-11394-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-STAT5A/ARNTL2-11394-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-STAT5A/ARNTL2-11394-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-STAT5A/ARNTL2-11394-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-STAT5A/ARNTL2-11394-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-STAT5A/ARNTL2-11394-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-STAT5A/ARNTL2-11394-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-STAT5A/ARNTL2-11394-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-STAT5A/ARNTL2-11394-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-STAT5A/ARNTL2-11394-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-STAT5A/ARNTL2-11394-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-STAT5A/ARNTL2-11394-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-STAT5A/ARNTL2-11394-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-STAT5A/ARNTL2-11394-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-STAT5A/ARNTL2-11394-AQAQ 467nm;467nm 418nm;418nm

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