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STAT3-NOS2 Gene Fusion FISH Probe

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Catalog: GFFP-STAT3/NOS2-11397
Classification: Gene Fusion FISH Probes
Description: The STAT3-NOS2 Gene Fusion FISH Probecan detect the fusion of STAT3 and NOS2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: STAT3-NOS2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Nitric Oxide Synthase 2
Gene Summary 1 Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 17
Locus 1 17q11.2
Coordinates 1 This gene maps to 26083791-26127555 in GRCh37 coordinates.
Gene Name 2 Signal Transducer And Activator Of Transcription 3
Gene Summary 2 The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]
Chromosome 2 Chromosome17
Locus 2 17q21.2
Coordinates 2 This gene maps to 40465342-40540513 in GRCh37 coordinates.
Associated Diseases Esophageal Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-STAT3/NOS2-11397-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-STAT3/NOS2-11397-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-STAT3/NOS2-11397-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-STAT3/NOS2-11397-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-STAT3/NOS2-11397-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-STAT3/NOS2-11397-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-STAT3/NOS2-11397-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-STAT3/NOS2-11397-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-STAT3/NOS2-11397-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-STAT3/NOS2-11397-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-STAT3/NOS2-11397-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-STAT3/NOS2-11397-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-STAT3/NOS2-11397-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-STAT3/NOS2-11397-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-STAT3/NOS2-11397-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-STAT3/NOS2-11397-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-STAT3/NOS2-11397-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-STAT3/NOS2-11397-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-STAT3/NOS2-11397-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-STAT3/NOS2-11397-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-STAT3/NOS2-11397-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-STAT3/NOS2-11397-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-STAT3/NOS2-11397-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-STAT3/NOS2-11397-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-STAT3/NOS2-11397-AQAQ 467nm;467nm 418nm;418nm

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