ST5-DENND5A Gene Fusion FISH Probe
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Catalog: |
GFFP-ST5/DENND5A-15605 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ST5-DENND5A Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ST5-DENND5A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Suppression Of Tumorigenicity 5 |
Gene Summary 1 |
This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11p15.4 |
Coordinates 1 |
This gene maps to 8714898-8932498in GRCh37 coordinates. |
Gene Name 2 |
DENN Domain Containing 5A |
Gene Summary 2 |
This gene encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene are associated with early infantile epileptic encephalopathy-49. [provided by RefSeq, Feb 2017] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11p15.4 |
Coordinates 2 |
This gene maps to 9160374-9286873 in GRCh37 coordinates. |
Associated Diseases |
Skin Cutaneous Melanoma; Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ST5/DENND5A-15605-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ST5/DENND5A-15605-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ST5/DENND5A-15605-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ST5/DENND5A-15605-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ST5/DENND5A-15605-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ST5/DENND5A-15605-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ST5/DENND5A-15605-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ST5/DENND5A-15605-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ST5/DENND5A-15605-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ST5/DENND5A-15605-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ST5/DENND5A-15605-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ST5/DENND5A-15605-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ST5/DENND5A-15605-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ST5/DENND5A-15605-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ST5/DENND5A-15605-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ST5/DENND5A-15605-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ST5/DENND5A-15605-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ST5/DENND5A-15605-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ST5/DENND5A-15605-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ST5/DENND5A-15605-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ST5/DENND5A-15605-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ST5/DENND5A-15605-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ST5/DENND5A-15605-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ST5/DENND5A-15605-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ST5/DENND5A-15605-AQAQ |
467nm;467nm |
418nm;418nm |
|
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