SREBF1-MED9 Gene Fusion FISH Probe
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Catalog: |
GFFP-SREBF1/MED9-11490 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SREBF1-MED9 Gene Fusion FISH Probecan detect the fusion of SREBF1 and MED9 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SREBF1-MED9 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Sterol Regulatory Element Binding Transcription Factor 1 |
Gene Summary 1 |
This gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis. The encoded protein is synthesized as a precursor that is initially attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription. This cleaveage is inhibited by sterols. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative promoter usage and splicing result in multiple transcript variants, including SREBP-1a and SREBP-1c, which correspond to RefSeq transcript variants 2 and 3, respectively. [provided by RefSeq, Nov 2017] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17p11.2 |
Coordinates 1 |
This gene maps to 17714662-17740325 in GRCh37 coordinates. |
Gene Name 2 |
Mediator Complex Subunit 9 |
Gene Summary 2 |
The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. The protein encoded by this gene is thought to be a subunit of the Mediator complex. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome17 |
Locus 2 |
17p11.2 |
Coordinates 2 |
This gene maps to 17380299-17396534 in GRCh37 coordinates. |
Associated Diseases |
Bladder Urothelial Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SREBF1/MED9-11490-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SREBF1/MED9-11490-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SREBF1/MED9-11490-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SREBF1/MED9-11490-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SREBF1/MED9-11490-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SREBF1/MED9-11490-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SREBF1/MED9-11490-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SREBF1/MED9-11490-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SREBF1/MED9-11490-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SREBF1/MED9-11490-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SREBF1/MED9-11490-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SREBF1/MED9-11490-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SREBF1/MED9-11490-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SREBF1/MED9-11490-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SREBF1/MED9-11490-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SREBF1/MED9-11490-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SREBF1/MED9-11490-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SREBF1/MED9-11490-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SREBF1/MED9-11490-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SREBF1/MED9-11490-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SREBF1/MED9-11490-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SREBF1/MED9-11490-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SREBF1/MED9-11490-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SREBF1/MED9-11490-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SREBF1/MED9-11490-AQAQ |
467nm;467nm |
418nm;418nm |
|
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