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SPAG1-ANGPT1 Gene Fusion FISH Probe

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Catalog: GFFP-SPAG1/ANGPT1-11290
Classification: Gene Fusion FISH Probes
Description: The SPAG1-ANGPT1 Gene Fusion FISH Probecan detect the fusion of SPAG1 and ANGPT1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SPAG1-ANGPT1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Angiopoietin 1
Gene Summary 1 This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]
Chromosome 1 Chromosome 8
Locus 1 8q23.1
Coordinates 1 This gene maps to 108261709-108510254 in GRCh37 coordinates.
Gene Name 2 Sperm Associated Antigen 1
Gene Summary 2 The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome8
Locus 2 8q22.2
Coordinates 2 This gene maps to 101170262-101254132 in GRCh37 coordinates.
Associated Diseases Sarcoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SPAG1/ANGPT1-11290-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SPAG1/ANGPT1-11290-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SPAG1/ANGPT1-11290-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SPAG1/ANGPT1-11290-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SPAG1/ANGPT1-11290-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SPAG1/ANGPT1-11290-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SPAG1/ANGPT1-11290-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SPAG1/ANGPT1-11290-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SPAG1/ANGPT1-11290-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SPAG1/ANGPT1-11290-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SPAG1/ANGPT1-11290-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SPAG1/ANGPT1-11290-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SPAG1/ANGPT1-11290-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SPAG1/ANGPT1-11290-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SPAG1/ANGPT1-11290-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SPAG1/ANGPT1-11290-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SPAG1/ANGPT1-11290-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SPAG1/ANGPT1-11290-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SPAG1/ANGPT1-11290-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SPAG1/ANGPT1-11290-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SPAG1/ANGPT1-11290-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SPAG1/ANGPT1-11290-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SPAG1/ANGPT1-11290-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SPAG1/ANGPT1-11290-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SPAG1/ANGPT1-11290-AQAQ 467nm;467nm 418nm;418nm

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