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SORL1-LMNA Gene Fusion FISH Probe

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Catalog: GFFP-SORL1/LMNA-11317
Classification: Gene Fusion FISH Probes
Description: The SORL1-LMNA Gene Fusion FISH Probecan detect the fusion of SORL1 and LMNA genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SORL1-LMNA Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Lamin A/C
Gene Summary 1 The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
Chromosome 1 Chromosome 1
Locus 1 1q22
Coordinates 1 This gene maps to 156084460-156109878 in GRCh37 coordinates.
Gene Name 2 Sortilin Related Receptor 1
Gene Summary 2 This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease. [provided by RefSeq, Feb 2016]
Chromosome 2 Chromosome11
Locus 2 11q24.1
Coordinates 2 This gene maps to 121322911-121504471 in GRCh37 coordinates.
Associated Diseases Brain Lower Grade Glioma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SORL1/LMNA-11317-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SORL1/LMNA-11317-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SORL1/LMNA-11317-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SORL1/LMNA-11317-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SORL1/LMNA-11317-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SORL1/LMNA-11317-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SORL1/LMNA-11317-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SORL1/LMNA-11317-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SORL1/LMNA-11317-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SORL1/LMNA-11317-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SORL1/LMNA-11317-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SORL1/LMNA-11317-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SORL1/LMNA-11317-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SORL1/LMNA-11317-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SORL1/LMNA-11317-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SORL1/LMNA-11317-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SORL1/LMNA-11317-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SORL1/LMNA-11317-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SORL1/LMNA-11317-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SORL1/LMNA-11317-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SORL1/LMNA-11317-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SORL1/LMNA-11317-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SORL1/LMNA-11317-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SORL1/LMNA-11317-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SORL1/LMNA-11317-AQAQ 467nm;467nm 418nm;418nm

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