SOCS6-PMS1 Gene Fusion FISH Probe
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Catalog: |
GFFP-SOCS6/PMS1-11336 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SOCS6-PMS1 Gene Fusion FISH Probecan detect the fusion of SOCS6 and PMS1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SOCS6-PMS1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
PMS1 Homolog 1, Mismatch Repair System Component |
Gene Summary 1 |
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 2 |
Locus 1 |
2q32.2 |
Coordinates 1 |
This gene maps to 190648810-190742355 in GRCh37 coordinates. |
Gene Name 2 |
Suppressor Of Cytokine Signaling 6 |
Gene Summary 2 |
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome18 |
Locus 2 |
18q22.2 |
Coordinates 2 |
This gene maps to 67956136-67997434 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SOCS6/PMS1-11336-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SOCS6/PMS1-11336-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SOCS6/PMS1-11336-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SOCS6/PMS1-11336-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SOCS6/PMS1-11336-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SOCS6/PMS1-11336-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SOCS6/PMS1-11336-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SOCS6/PMS1-11336-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SOCS6/PMS1-11336-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SOCS6/PMS1-11336-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SOCS6/PMS1-11336-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SOCS6/PMS1-11336-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SOCS6/PMS1-11336-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SOCS6/PMS1-11336-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SOCS6/PMS1-11336-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SOCS6/PMS1-11336-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SOCS6/PMS1-11336-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SOCS6/PMS1-11336-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SOCS6/PMS1-11336-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SOCS6/PMS1-11336-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SOCS6/PMS1-11336-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SOCS6/PMS1-11336-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SOCS6/PMS1-11336-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SOCS6/PMS1-11336-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SOCS6/PMS1-11336-AQAQ |
467nm;467nm |
418nm;418nm |
|
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