SOCS5-SLC8A1 Gene Fusion FISH Probe
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Catalog: |
GFFP-SOCS5/SLC8A1-11340 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SOCS5-SLC8A1 Gene Fusion FISH Probecan detect the fusion of SOCS5 and SLC8A1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SOCS5-SLC8A1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Solute Carrier Family 8 Member A1 |
Gene Summary 1 |
In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM, Apr 2004] |
Chromosome 1 |
Chromosome 2 |
Locus 1 |
2p22.1 |
Coordinates 1 |
This gene maps to 40339285-40739575 in GRCh37 coordinates. |
Gene Name 2 |
Suppressor Of Cytokine Signaling 5 |
Gene Summary 2 |
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome2 |
Locus 2 |
2p21 |
Coordinates 2 |
This gene maps to 46926098-46989927 in GRCh37 coordinates. |
Associated Diseases |
Liver Hepatocellular Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SOCS5/SLC8A1-11340-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SOCS5/SLC8A1-11340-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SOCS5/SLC8A1-11340-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SOCS5/SLC8A1-11340-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SOCS5/SLC8A1-11340-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SOCS5/SLC8A1-11340-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SOCS5/SLC8A1-11340-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SOCS5/SLC8A1-11340-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SOCS5/SLC8A1-11340-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SOCS5/SLC8A1-11340-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SOCS5/SLC8A1-11340-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SOCS5/SLC8A1-11340-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SOCS5/SLC8A1-11340-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SOCS5/SLC8A1-11340-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SOCS5/SLC8A1-11340-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SOCS5/SLC8A1-11340-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SOCS5/SLC8A1-11340-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SOCS5/SLC8A1-11340-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SOCS5/SLC8A1-11340-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SOCS5/SLC8A1-11340-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SOCS5/SLC8A1-11340-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SOCS5/SLC8A1-11340-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SOCS5/SLC8A1-11340-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SOCS5/SLC8A1-11340-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SOCS5/SLC8A1-11340-AQAQ |
467nm;467nm |
418nm;418nm |
|
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