SND1-BRAF Gene Fusion FISH Probe
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Catalog: |
GFFP-SND1/BRAF-15575 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SND1-BRAF Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SND1-BRAF Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
B-Raf Proto-oncogene, Serine/threonine Kinase |
Gene Summary 1 |
This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017] |
Chromosome 1 |
Chromosome 7 |
Locus 1 |
7q34 |
Coordinates 1 |
This gene maps to 140433812-140624564in GRCh37 coordinates. |
Gene Name 2 |
Staphylococcal Nuclease And Tudor Domain Containing 1 |
Gene Summary 2 |
This gene encodes a transcriptional co-activator that interacts with the acidic domain of Epstein-Barr virus nuclear antigen 2 (EBNA 2), a transcriptional activator that is required for B-lymphocyte transformation. Other transcription factors that interact with this protein are signal transducers and activators of transcription, STATs. This protein is also thought to be essential for normal cell growth. A similar protein in mammals and other organisms is a component of the RNA-induced silencing complex (RISC). [provided by RefSeq, Jul 2016] |
Chromosome 2 |
Chromosome7 |
Locus 2 |
7q32.1 |
Coordinates 2 |
This gene maps to 127292201-127732659 in GRCh37 coordinates. |
Associated Diseases |
Thyroid Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SND1/BRAF-15575-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SND1/BRAF-15575-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SND1/BRAF-15575-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SND1/BRAF-15575-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SND1/BRAF-15575-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SND1/BRAF-15575-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SND1/BRAF-15575-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SND1/BRAF-15575-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SND1/BRAF-15575-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SND1/BRAF-15575-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SND1/BRAF-15575-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SND1/BRAF-15575-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SND1/BRAF-15575-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SND1/BRAF-15575-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SND1/BRAF-15575-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SND1/BRAF-15575-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SND1/BRAF-15575-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SND1/BRAF-15575-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SND1/BRAF-15575-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SND1/BRAF-15575-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SND1/BRAF-15575-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SND1/BRAF-15575-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SND1/BRAF-15575-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SND1/BRAF-15575-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SND1/BRAF-15575-AQAQ |
467nm;467nm |
418nm;418nm |
|
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