SMURF1-DNAJC2 Gene Fusion FISH Probe
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Catalog: |
GFFP-SMURF1/DNAJC2-11130 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SMURF1-DNAJC2 Gene Fusion FISH Probecan detect the fusion of SMURF1 and DNAJC2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SMURF1-DNAJC2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
DnaJ Heat Shock Protein Family (Hsp40) Member C2 |
Gene Summary 1 |
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 7 |
Locus 1 |
7q22.1 |
Coordinates 1 |
This gene maps to 102952920-102985320 in GRCh37 coordinates. |
Gene Name 2 |
SMAD Specific E3 Ubiquitin Protein Ligase 1 |
Gene Summary 2 |
This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2010] |
Chromosome 2 |
Chromosome7 |
Locus 2 |
7q22.1 |
Coordinates 2 |
This gene maps to 98625057-98741743 in GRCh37 coordinates. |
Associated Diseases |
Lung Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SMURF1/DNAJC2-11130-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SMURF1/DNAJC2-11130-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SMURF1/DNAJC2-11130-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SMURF1/DNAJC2-11130-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SMURF1/DNAJC2-11130-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SMURF1/DNAJC2-11130-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SMURF1/DNAJC2-11130-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SMURF1/DNAJC2-11130-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SMURF1/DNAJC2-11130-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SMURF1/DNAJC2-11130-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SMURF1/DNAJC2-11130-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SMURF1/DNAJC2-11130-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SMURF1/DNAJC2-11130-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SMURF1/DNAJC2-11130-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SMURF1/DNAJC2-11130-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SMURF1/DNAJC2-11130-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SMURF1/DNAJC2-11130-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SMURF1/DNAJC2-11130-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SMURF1/DNAJC2-11130-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SMURF1/DNAJC2-11130-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SMURF1/DNAJC2-11130-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SMURF1/DNAJC2-11130-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SMURF1/DNAJC2-11130-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SMURF1/DNAJC2-11130-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SMURF1/DNAJC2-11130-AQAQ |
467nm;467nm |
418nm;418nm |
|
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