SMG6-SHPK Gene Fusion FISH Probe
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Catalog: |
GFFP-SMG6/SHPK-11145 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SMG6-SHPK Gene Fusion FISH Probecan detect the fusion of SMG6 and SHPK genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SMG6-SHPK Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
SMG6, Nonsense Mediated MRNA Decay Factor |
Gene Summary 1 |
This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described. [provided by RefSeq, Feb 2014] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17p13.3 |
Coordinates 1 |
This gene maps to 1963132-2207069 in GRCh37 coordinates. |
Gene Name 2 |
Sedoheptulokinase |
Gene Summary 2 |
The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome17 |
Locus 2 |
17p13.2 |
Coordinates 2 |
This gene maps to 3511555-3539616 in GRCh37 coordinates. |
Associated Diseases |
Prostate Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SMG6/SHPK-11145-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SMG6/SHPK-11145-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SMG6/SHPK-11145-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SMG6/SHPK-11145-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SMG6/SHPK-11145-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SMG6/SHPK-11145-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SMG6/SHPK-11145-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SMG6/SHPK-11145-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SMG6/SHPK-11145-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SMG6/SHPK-11145-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SMG6/SHPK-11145-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SMG6/SHPK-11145-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SMG6/SHPK-11145-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SMG6/SHPK-11145-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SMG6/SHPK-11145-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SMG6/SHPK-11145-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SMG6/SHPK-11145-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SMG6/SHPK-11145-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SMG6/SHPK-11145-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SMG6/SHPK-11145-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SMG6/SHPK-11145-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SMG6/SHPK-11145-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SMG6/SHPK-11145-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SMG6/SHPK-11145-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SMG6/SHPK-11145-AQAQ |
467nm;467nm |
418nm;418nm |
|
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