SMG1-SNF8 Gene Fusion FISH Probe
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Catalog: |
GFFP-SMG1/SNF8-11155 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SMG1-SNF8 Gene Fusion FISH Probecan detect the fusion of SMG1 and SNF8 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SMG1-SNF8 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
SNF8, ESCRT-II Complex Subunit |
Gene Summary 1 |
The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17q21.32 |
Coordinates 1 |
This gene maps to 47007458-47022154 in GRCh37 coordinates. |
Gene Name 2 |
SMG1, Nonsense Mediated MRNA Decay Associated PI3K Related Kinase |
Gene Summary 2 |
This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternatively spliced transcript variants have been described, but their full-length nature has yet to be determined. [provided by RefSeq, Mar 2013] |
Chromosome 2 |
Chromosome16 |
Locus 2 |
16p12.3 |
Coordinates 2 |
This gene maps to 18816174-18937726 in GRCh37 coordinates. |
Associated Diseases |
Prostate Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
RE; RE
|
GFFP-SMG1/SNF8-11155-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SMG1/SNF8-11155-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SMG1/SNF8-11155-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SMG1/SNF8-11155-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SMG1/SNF8-11155-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SMG1/SNF8-11155-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SMG1/SNF8-11155-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SMG1/SNF8-11155-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SMG1/SNF8-11155-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SMG1/SNF8-11155-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SMG1/SNF8-11155-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SMG1/SNF8-11155-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SMG1/SNF8-11155-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SMG1/SNF8-11155-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SMG1/SNF8-11155-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SMG1/SNF8-11155-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SMG1/SNF8-11155-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SMG1/SNF8-11155-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SMG1/SNF8-11155-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SMG1/SNF8-11155-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SMG1/SNF8-11155-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SMG1/SNF8-11155-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SMG1/SNF8-11155-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SMG1/SNF8-11155-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SMG1/SNF8-11155-AQAQ |
467nm;467nm |
418nm;418nm |
|
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