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SMARCC1-DOCK3 Gene Fusion FISH Probe

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Catalog: GFFP-SMARCC1/DOCK3-11185
Classification: Gene Fusion FISH Probes
Description: The SMARCC1-DOCK3 Gene Fusion FISH Probecan detect the fusion of SMARCC1 and DOCK3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SMARCC1-DOCK3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Dedicator Of Cytokinesis 3
Gene Summary 1 This gene is specifically expressed in the central nervous system (CNS). It encodes a member of the DOCK (dedicator of cytokinesis) family of guanine nucleotide exchange factors (GEFs). This protein, dedicator of cytokinesis 3 (DOCK3), is also known as modifier of cell adhesion (MOCA) and presenilin-binding protein (PBP). The DOCK3 and DOCK1, -2 and -4 share several conserved amino acids in their DHR-2 (DOCK homology region 2) domains that are required for GEF activity, and bind directly to WAVE proteins [Wiskott-Aldrich syndrome protein (WASP) family Verprolin-homologous proteins] via their DHR-1 domains. The DOCK3 induces axonal outgrowth in CNS by stimulating membrane recruitment of the WAVE complex and activating the small G protein Rac1. This gene is associated with an attention deficit hyperactivity disorder-like phenotype by a complex chromosomal rearrangement. [provided by RefSeq, Aug 2010]
Chromosome 1 Chromosome 3
Locus 1 3p21.2
Coordinates 1 This gene maps to 50712671-51421629 in GRCh37 coordinates.
Gene Name 2 SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin Subfamily C Member 1
Gene Summary 2 The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome3
Locus 2 3p21.31
Coordinates 2 This gene maps to 47627377-47823405 in GRCh37 coordinates.
Associated Diseases Bladder Urothelial Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SMARCC1/DOCK3-11185-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SMARCC1/DOCK3-11185-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SMARCC1/DOCK3-11185-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SMARCC1/DOCK3-11185-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SMARCC1/DOCK3-11185-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SMARCC1/DOCK3-11185-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SMARCC1/DOCK3-11185-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SMARCC1/DOCK3-11185-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SMARCC1/DOCK3-11185-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SMARCC1/DOCK3-11185-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SMARCC1/DOCK3-11185-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SMARCC1/DOCK3-11185-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SMARCC1/DOCK3-11185-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SMARCC1/DOCK3-11185-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SMARCC1/DOCK3-11185-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SMARCC1/DOCK3-11185-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SMARCC1/DOCK3-11185-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SMARCC1/DOCK3-11185-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SMARCC1/DOCK3-11185-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SMARCC1/DOCK3-11185-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SMARCC1/DOCK3-11185-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SMARCC1/DOCK3-11185-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SMARCC1/DOCK3-11185-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SMARCC1/DOCK3-11185-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SMARCC1/DOCK3-11185-AQAQ 467nm;467nm 418nm;418nm

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