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SMARCA4-RNF216 Gene Fusion FISH Probe

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Catalog: GFFP-SMARCA4/RNF216-11074
Classification: Gene Fusion FISH Probes
Description: The SMARCA4-RNF216 Gene Fusion FISH Probecan detect the fusion of SMARCA4 and RNF216 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SMARCA4-RNF216 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 4
Gene Summary 1 The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Chromosome 1 Chromosome 19
Locus 1 19p13.2
Coordinates 1 This gene maps to 11071597-11172958 in GRCh37 coordinates.
Gene Name 2 Ring Finger Protein 216
Gene Summary 2 This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome7
Locus 2 7p22.1
Coordinates 2 This gene maps to 5659671-5821361 in GRCh37 coordinates.
Associated Diseases Uterine Carcinosarcoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SMARCA4/RNF216-11074-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SMARCA4/RNF216-11074-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SMARCA4/RNF216-11074-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SMARCA4/RNF216-11074-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SMARCA4/RNF216-11074-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SMARCA4/RNF216-11074-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SMARCA4/RNF216-11074-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SMARCA4/RNF216-11074-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SMARCA4/RNF216-11074-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SMARCA4/RNF216-11074-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SMARCA4/RNF216-11074-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SMARCA4/RNF216-11074-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SMARCA4/RNF216-11074-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SMARCA4/RNF216-11074-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SMARCA4/RNF216-11074-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SMARCA4/RNF216-11074-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SMARCA4/RNF216-11074-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SMARCA4/RNF216-11074-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SMARCA4/RNF216-11074-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SMARCA4/RNF216-11074-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SMARCA4/RNF216-11074-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SMARCA4/RNF216-11074-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SMARCA4/RNF216-11074-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SMARCA4/RNF216-11074-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SMARCA4/RNF216-11074-AQAQ 467nm;467nm 418nm;418nm

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