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SMAD2-ZBTB7C Gene Fusion FISH Probe

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Catalog: GFFP-SMAD2/ZBTB7C-15586
Classification: Gene Fusion FISH Probes
Description: The SMAD2-ZBTB7C Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SMAD2-ZBTB7C Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 SMAD Family Member 2
Gene Summary 1 The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
Chromosome 1 Chromosome 18
Locus 1 18q21.1
Coordinates 1 This gene maps to 45359465-45457515in GRCh37 coordinates.
Gene Name 2 Zinc Finger And BTB Domain Containing 7C
Gene Summary 2 The Zinc Finger And BTB Domain Containing 7C (ZBTB7C) gene is located on chr18 :45553638-45663680 at 18q21.1.
Chromosome 2 Chromosome18
Locus 2 18q21.1
Coordinates 2 This gene maps to 45553638-45663680 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma; Adrenocortical Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SMAD2/ZBTB7C-15586-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SMAD2/ZBTB7C-15586-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SMAD2/ZBTB7C-15586-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SMAD2/ZBTB7C-15586-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SMAD2/ZBTB7C-15586-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SMAD2/ZBTB7C-15586-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SMAD2/ZBTB7C-15586-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SMAD2/ZBTB7C-15586-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SMAD2/ZBTB7C-15586-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SMAD2/ZBTB7C-15586-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SMAD2/ZBTB7C-15586-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SMAD2/ZBTB7C-15586-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SMAD2/ZBTB7C-15586-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SMAD2/ZBTB7C-15586-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SMAD2/ZBTB7C-15586-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SMAD2/ZBTB7C-15586-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SMAD2/ZBTB7C-15586-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SMAD2/ZBTB7C-15586-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SMAD2/ZBTB7C-15586-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SMAD2/ZBTB7C-15586-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SMAD2/ZBTB7C-15586-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SMAD2/ZBTB7C-15586-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SMAD2/ZBTB7C-15586-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SMAD2/ZBTB7C-15586-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SMAD2/ZBTB7C-15586-AQAQ 467nm;467nm 418nm;418nm

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