SKI-PRKCZ Gene Fusion FISH Probe
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Catalog: |
GFFP-SKI/PRKCZ-10738 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SKI-PRKCZ Gene Fusion FISH Probecan detect the fusion of SKI and PRKCZ genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SKI-PRKCZ Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Protein Kinase C Zeta |
Gene Summary 1 |
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 1 |
Locus 1 |
1p36.33 |
Coordinates 1 |
This gene maps to 1981908-2116834 in GRCh37 coordinates. |
Gene Name 2 |
SKI Proto-oncogene |
Gene Summary 2 |
This gene encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation. [provided by RefSeq, Oct 2009] |
Chromosome 2 |
Chromosome1 |
Locus 2 |
1p36.33-p36.32 |
Coordinates 2 |
This gene maps to 2160133-2241652 in GRCh37 coordinates. |
Associated Diseases |
Bladder Urothelial Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SKI/PRKCZ-10738-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SKI/PRKCZ-10738-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SKI/PRKCZ-10738-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SKI/PRKCZ-10738-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SKI/PRKCZ-10738-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SKI/PRKCZ-10738-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SKI/PRKCZ-10738-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SKI/PRKCZ-10738-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SKI/PRKCZ-10738-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SKI/PRKCZ-10738-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SKI/PRKCZ-10738-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SKI/PRKCZ-10738-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SKI/PRKCZ-10738-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SKI/PRKCZ-10738-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SKI/PRKCZ-10738-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SKI/PRKCZ-10738-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SKI/PRKCZ-10738-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SKI/PRKCZ-10738-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SKI/PRKCZ-10738-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SKI/PRKCZ-10738-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SKI/PRKCZ-10738-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SKI/PRKCZ-10738-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SKI/PRKCZ-10738-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SKI/PRKCZ-10738-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SKI/PRKCZ-10738-AQAQ |
467nm;467nm |
418nm;418nm |
|
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