SIPA1L3-ERC1 Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-SIPA1L3/ERC1-10761 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SIPA1L3-ERC1 Gene Fusion FISH Probecan detect the fusion of SIPA1L3 and ERC1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SIPA1L3-ERC1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
ELKS/RAB6-interacting/CAST Family Member 1 |
Gene Summary 1 |
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12p13.33 |
Coordinates 1 |
This gene maps to 1100403-1605099 in GRCh37 coordinates. |
Gene Name 2 |
Signal Induced Proliferation Associated 1 Like 3 |
Gene Summary 2 |
This gene belongs to the signal induced proliferation associated 1 family of genes, which encode GTPase-activating proteins specific for the GTP-binding protein Rap1. Rap1 has been implicated in regulation of cell adhesion, cell polarity, and organization of the cytoskeleton. Like other members of the family, the protein encoded by this gene contains RapGAP and PDZ domains. In addition, this protein contains a C-terminal leucine zipper domain. This gene is proposed to function in epithelial cell morphogenesis and establishment or maintenance of polarity. Consistently, expression of the protein in cell culture showed localization to cell-cell borders in apical regions, and downregulation of the gene in 3D Caco2 cell culture resulted in abnormal cell polarity and morphogenesis. Allelic variants of this gene have been associated with congenital cataracts in humans. [provided by RefSeq, Feb 2016] |
Chromosome 2 |
Chromosome19 |
Locus 2 |
19q13.13-q13.2 |
Coordinates 2 |
This gene maps to 38397867-38699008 in GRCh37 coordinates. |
Associated Diseases |
Ovarian Serous Cystadenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SIPA1L3/ERC1-10761-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SIPA1L3/ERC1-10761-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SIPA1L3/ERC1-10761-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SIPA1L3/ERC1-10761-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SIPA1L3/ERC1-10761-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SIPA1L3/ERC1-10761-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SIPA1L3/ERC1-10761-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SIPA1L3/ERC1-10761-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SIPA1L3/ERC1-10761-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SIPA1L3/ERC1-10761-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SIPA1L3/ERC1-10761-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SIPA1L3/ERC1-10761-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SIPA1L3/ERC1-10761-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SIPA1L3/ERC1-10761-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SIPA1L3/ERC1-10761-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SIPA1L3/ERC1-10761-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SIPA1L3/ERC1-10761-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SIPA1L3/ERC1-10761-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SIPA1L3/ERC1-10761-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SIPA1L3/ERC1-10761-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SIPA1L3/ERC1-10761-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SIPA1L3/ERC1-10761-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SIPA1L3/ERC1-10761-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SIPA1L3/ERC1-10761-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SIPA1L3/ERC1-10761-AQAQ |
467nm;467nm |
418nm;418nm |
|
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