SIM2-KCNJ6 Gene Fusion FISH Probe
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Catalog: |
GFFP-SIM2/KCNJ6-10776 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SIM2-KCNJ6 Gene Fusion FISH Probecan detect the fusion of SIM2 and KCNJ6 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SIM2-KCNJ6 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Potassium Voltage-gated Channel Subfamily J Member 6 |
Gene Summary 1 |
This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015] |
Chromosome 1 |
Chromosome 21 |
Locus 1 |
21q22.13 |
Coordinates 1 |
This gene maps to 38996785-39288696 in GRCh37 coordinates. |
Gene Name 2 |
Single-minded Family BHLH Transcription Factor 2 |
Gene Summary 2 |
This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
Chromosome 2 |
Chromosome21 |
Locus 2 |
21q22.13 |
Coordinates 2 |
This gene maps to 38071990-38122510 in GRCh37 coordinates. |
Associated Diseases |
Brain Lower Grade Glioma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SIM2/KCNJ6-10776-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SIM2/KCNJ6-10776-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SIM2/KCNJ6-10776-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SIM2/KCNJ6-10776-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SIM2/KCNJ6-10776-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SIM2/KCNJ6-10776-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SIM2/KCNJ6-10776-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SIM2/KCNJ6-10776-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SIM2/KCNJ6-10776-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SIM2/KCNJ6-10776-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SIM2/KCNJ6-10776-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SIM2/KCNJ6-10776-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SIM2/KCNJ6-10776-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SIM2/KCNJ6-10776-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SIM2/KCNJ6-10776-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SIM2/KCNJ6-10776-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SIM2/KCNJ6-10776-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SIM2/KCNJ6-10776-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SIM2/KCNJ6-10776-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SIM2/KCNJ6-10776-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SIM2/KCNJ6-10776-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SIM2/KCNJ6-10776-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SIM2/KCNJ6-10776-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SIM2/KCNJ6-10776-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SIM2/KCNJ6-10776-AQAQ |
467nm;467nm |
418nm;418nm |
|
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