SHANK2-WNT11 Gene Fusion FISH Probe
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Catalog: |
GFFP-SHANK2/WNT11-10838 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SHANK2-WNT11 Gene Fusion FISH Probecan detect the fusion of SHANK2 and WNT11 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SHANK2-WNT11 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Wnt Family Member 11 |
Gene Summary 1 |
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11q13.5 |
Coordinates 1 |
This gene maps to 75897369-75917574 in GRCh37 coordinates. |
Gene Name 2 |
SH3 And Multiple Ankyrin Repeat Domains 2 |
Gene Summary 2 |
This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density of excitatory synapses. Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, and an SH3 domain. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the postsynaptic densities of the adult and developing brain. Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11q13.3-q13.4 |
Coordinates 2 |
This gene maps to 70313960-70935808 in GRCh37 coordinates. |
Associated Diseases |
Lung Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SHANK2/WNT11-10838-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SHANK2/WNT11-10838-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SHANK2/WNT11-10838-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SHANK2/WNT11-10838-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SHANK2/WNT11-10838-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SHANK2/WNT11-10838-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SHANK2/WNT11-10838-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SHANK2/WNT11-10838-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SHANK2/WNT11-10838-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SHANK2/WNT11-10838-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SHANK2/WNT11-10838-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SHANK2/WNT11-10838-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SHANK2/WNT11-10838-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SHANK2/WNT11-10838-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SHANK2/WNT11-10838-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SHANK2/WNT11-10838-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SHANK2/WNT11-10838-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SHANK2/WNT11-10838-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SHANK2/WNT11-10838-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SHANK2/WNT11-10838-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SHANK2/WNT11-10838-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SHANK2/WNT11-10838-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SHANK2/WNT11-10838-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SHANK2/WNT11-10838-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SHANK2/WNT11-10838-AQAQ |
467nm;467nm |
418nm;418nm |
|
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