SERPINA3-EIF2AK2 Gene Fusion FISH Probe
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Catalog: |
GFFP-SERPINA3/EIF2AK2-10632 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SERPINA3-EIF2AK2 Gene Fusion FISH Probecan detect the fusion of SERPINA3 and EIF2AK2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SERPINA3-EIF2AK2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Serpin Family A Member 3 |
Gene Summary 1 |
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 14 |
Locus 1 |
14q32.13 |
Coordinates 1 |
This gene maps to 95078713-95090390 in GRCh37 coordinates. |
Gene Name 2 |
Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2 |
Gene Summary 2 |
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
Chromosome 2 |
Chromosome2 |
Locus 2 |
2p22.2 |
Coordinates 2 |
This gene maps to 37333698-37384190 in GRCh37 coordinates. |
Associated Diseases |
Liver Hepatocellular Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SERPINA3/EIF2AK2-10632-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SERPINA3/EIF2AK2-10632-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SERPINA3/EIF2AK2-10632-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SERPINA3/EIF2AK2-10632-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SERPINA3/EIF2AK2-10632-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SERPINA3/EIF2AK2-10632-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SERPINA3/EIF2AK2-10632-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SERPINA3/EIF2AK2-10632-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SERPINA3/EIF2AK2-10632-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SERPINA3/EIF2AK2-10632-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SERPINA3/EIF2AK2-10632-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SERPINA3/EIF2AK2-10632-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SERPINA3/EIF2AK2-10632-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SERPINA3/EIF2AK2-10632-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SERPINA3/EIF2AK2-10632-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SERPINA3/EIF2AK2-10632-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SERPINA3/EIF2AK2-10632-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SERPINA3/EIF2AK2-10632-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SERPINA3/EIF2AK2-10632-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SERPINA3/EIF2AK2-10632-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SERPINA3/EIF2AK2-10632-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SERPINA3/EIF2AK2-10632-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SERPINA3/EIF2AK2-10632-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SERPINA3/EIF2AK2-10632-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SERPINA3/EIF2AK2-10632-AQAQ |
467nm;467nm |
418nm;418nm |
|
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