SENP7-RFC4 Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-SENP7/RFC4-10649 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SENP7-RFC4 Gene Fusion FISH Probecan detect the fusion of SENP7 and RFC4 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SENP7-RFC4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Replication Factor C Subunit 4 |
Gene Summary 1 |
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 3 |
Locus 1 |
3q27.3 |
Coordinates 1 |
This gene maps to 186507681-186524484 in GRCh37 coordinates. |
Gene Name 2 |
SUMO1/sentrin Specific Peptidase 7 |
Gene Summary 2 |
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009] |
Chromosome 2 |
Chromosome3 |
Locus 2 |
3q12.3 |
Coordinates 2 |
This gene maps to 101043117-101232085 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SENP7/RFC4-10649-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SENP7/RFC4-10649-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SENP7/RFC4-10649-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SENP7/RFC4-10649-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SENP7/RFC4-10649-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SENP7/RFC4-10649-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SENP7/RFC4-10649-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SENP7/RFC4-10649-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SENP7/RFC4-10649-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SENP7/RFC4-10649-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SENP7/RFC4-10649-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SENP7/RFC4-10649-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SENP7/RFC4-10649-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SENP7/RFC4-10649-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SENP7/RFC4-10649-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SENP7/RFC4-10649-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SENP7/RFC4-10649-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SENP7/RFC4-10649-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SENP7/RFC4-10649-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SENP7/RFC4-10649-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SENP7/RFC4-10649-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SENP7/RFC4-10649-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SENP7/RFC4-10649-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SENP7/RFC4-10649-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SENP7/RFC4-10649-AQAQ |
467nm;467nm |
418nm;418nm |
|
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