SDC1-PLAT Gene Fusion FISH Probe
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Catalog: |
GFFP-SDC1/PLAT-14530 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SDC1-PLAT Gene Fusion FISH Probecan detect the fusion of SDC1 and PLAT genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SDC1-PLAT Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Plasminogen Activator, Tissue Type |
Gene Summary 1 |
This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] |
Chromosome 1 |
Chromosome 8 |
Locus 1 |
8p11.21 |
Coordinates 1 |
This gene maps to 42032235-42065194 in GRCh37 coordinates. |
Gene Name 2 |
Syndecan 1 |
Gene Summary 2 |
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome2 |
Locus 2 |
2p24.1 |
Coordinates 2 |
This gene maps to 20400557-20425194 in GRCh37 coordinates. |
Associated Diseases |
Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SDC1/PLAT-14530-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SDC1/PLAT-14530-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SDC1/PLAT-14530-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SDC1/PLAT-14530-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SDC1/PLAT-14530-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SDC1/PLAT-14530-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SDC1/PLAT-14530-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SDC1/PLAT-14530-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SDC1/PLAT-14530-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SDC1/PLAT-14530-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SDC1/PLAT-14530-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SDC1/PLAT-14530-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SDC1/PLAT-14530-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SDC1/PLAT-14530-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SDC1/PLAT-14530-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SDC1/PLAT-14530-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SDC1/PLAT-14530-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SDC1/PLAT-14530-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SDC1/PLAT-14530-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SDC1/PLAT-14530-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SDC1/PLAT-14530-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SDC1/PLAT-14530-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SDC1/PLAT-14530-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SDC1/PLAT-14530-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SDC1/PLAT-14530-AQAQ |
467nm;467nm |
418nm;418nm |
|
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