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SCUBE3-ANKS1A Gene Fusion FISH Probe

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Catalog: GFFP-SCUBE3/ANKS1A-15520
Classification: Gene Fusion FISH Probes
Description: The SCUBE3-ANKS1A Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SCUBE3-ANKS1A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Ankyrin Repeat And Sterile Alpha Motif Domain Containing 1A
Gene Summary 1 The Ankyrin Repeat And Sterile Alpha Motif Domain Containing 1A (ANKS1A) gene is located on chr6 :34857037-35059190 at 6p21.31.
Chromosome 1 Chromosome 6
Locus 1 6p21.31
Coordinates 1 This gene maps to 34857037-35059190in GRCh37 coordinates.
Gene Name 2 Signal Peptide, CUB Domain And EGF Like Domain Containing 3
Gene Summary 2 This gene encodes a member of the signal peptide, complement subcomponents C1r/C1s, Uegf, bone morphogenetic protein-1 and epidermal growth factor-like domain containing protein family. Overexpression of this gene in human embryonic kidney cells results in secretion of a glycosylated form of the protein that forms oligomers and tethers to the cell surface. This gene is upregulated in lung cancer tumor tissue compared to healthy tissue and is associated with loss of the epithelial marker E-cadherin and with increased expression of vimentin, a mesenchymal marker. In addition, the protein encoded by this gene is a transforming growth factor beta receptor ligand, and when secreted by cancer cells, it can be cleaved in vitro to release the N-terminal epidermal growth factor-like repeat domain and the C-terminal complement subcomponents C1r/C1s domain. Both the full length protein and C-terminal fragment can bind to the transforming growth factor beta type II receptor to promote the epithelial-mesenchymal transition and tumor angiogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Chromosome 2 Chromosome6
Locus 2 6p21.31
Coordinates 2 This gene maps to 35182189-35218609 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SCUBE3/ANKS1A-15520-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SCUBE3/ANKS1A-15520-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SCUBE3/ANKS1A-15520-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SCUBE3/ANKS1A-15520-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SCUBE3/ANKS1A-15520-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SCUBE3/ANKS1A-15520-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SCUBE3/ANKS1A-15520-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SCUBE3/ANKS1A-15520-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SCUBE3/ANKS1A-15520-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SCUBE3/ANKS1A-15520-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SCUBE3/ANKS1A-15520-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SCUBE3/ANKS1A-15520-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SCUBE3/ANKS1A-15520-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SCUBE3/ANKS1A-15520-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SCUBE3/ANKS1A-15520-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SCUBE3/ANKS1A-15520-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SCUBE3/ANKS1A-15520-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SCUBE3/ANKS1A-15520-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SCUBE3/ANKS1A-15520-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SCUBE3/ANKS1A-15520-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SCUBE3/ANKS1A-15520-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SCUBE3/ANKS1A-15520-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SCUBE3/ANKS1A-15520-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SCUBE3/ANKS1A-15520-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SCUBE3/ANKS1A-15520-AQAQ 467nm;467nm 418nm;418nm

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