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SCN8A-ATF1 Gene Fusion FISH Probe

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Catalog: GFFP-SCN8A/ATF1-10426
Classification: Gene Fusion FISH Probes
Description: The SCN8A-ATF1 Gene Fusion FISH Probecan detect the fusion of SCN8A and ATF1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SCN8A-ATF1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Activating Transcription Factor 1
Gene Summary 1 This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq, Aug 2010]
Chromosome 1 Chromosome 12
Locus 1 12q13.12
Coordinates 1 This gene maps to 51157788-51214943 in GRCh37 coordinates.
Gene Name 2 Sodium Voltage-gated Channel Alpha Subunit 8
Gene Summary 2 This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with cognitive disability, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Chromosome 2 Chromosome12
Locus 2 12q13.13
Coordinates 2 This gene maps to 51985019-52202299 in GRCh37 coordinates.
Associated Diseases Brain Lower Grade Glioma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SCN8A/ATF1-10426-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SCN8A/ATF1-10426-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SCN8A/ATF1-10426-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SCN8A/ATF1-10426-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SCN8A/ATF1-10426-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SCN8A/ATF1-10426-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SCN8A/ATF1-10426-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SCN8A/ATF1-10426-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SCN8A/ATF1-10426-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SCN8A/ATF1-10426-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SCN8A/ATF1-10426-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SCN8A/ATF1-10426-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SCN8A/ATF1-10426-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SCN8A/ATF1-10426-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SCN8A/ATF1-10426-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SCN8A/ATF1-10426-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SCN8A/ATF1-10426-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SCN8A/ATF1-10426-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SCN8A/ATF1-10426-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SCN8A/ATF1-10426-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SCN8A/ATF1-10426-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SCN8A/ATF1-10426-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SCN8A/ATF1-10426-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SCN8A/ATF1-10426-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SCN8A/ATF1-10426-AQAQ 467nm;467nm 418nm;418nm

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