SCD5-SEC31A Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-SCD5/SEC31A-10444 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SCD5-SEC31A Gene Fusion FISH Probecan detect the fusion of SCD5 and SEC31A genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SCD5-SEC31A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
SEC31 Homolog A, COPII Coat Complex Component |
Gene Summary 1 |
The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] |
Chromosome 1 |
Chromosome 4 |
Locus 1 |
4q21.22 |
Coordinates 1 |
This gene maps to 83739813-83812419 in GRCh37 coordinates. |
Gene Name 2 |
Stearoyl-CoA Desaturase 5 |
Gene Summary 2 |
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM, Mar 2008] |
Chromosome 2 |
Chromosome4 |
Locus 2 |
4q21.22 |
Coordinates 2 |
This gene maps to 83550689-83720010 in GRCh37 coordinates. |
Associated Diseases |
Adrenocortical Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SCD5/SEC31A-10444-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SCD5/SEC31A-10444-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SCD5/SEC31A-10444-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SCD5/SEC31A-10444-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SCD5/SEC31A-10444-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SCD5/SEC31A-10444-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SCD5/SEC31A-10444-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SCD5/SEC31A-10444-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SCD5/SEC31A-10444-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SCD5/SEC31A-10444-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SCD5/SEC31A-10444-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SCD5/SEC31A-10444-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SCD5/SEC31A-10444-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SCD5/SEC31A-10444-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SCD5/SEC31A-10444-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SCD5/SEC31A-10444-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SCD5/SEC31A-10444-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SCD5/SEC31A-10444-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SCD5/SEC31A-10444-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SCD5/SEC31A-10444-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SCD5/SEC31A-10444-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SCD5/SEC31A-10444-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SCD5/SEC31A-10444-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SCD5/SEC31A-10444-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SCD5/SEC31A-10444-AQAQ |
467nm;467nm |
418nm;418nm |
|
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