SBF2-MDM2 Gene Fusion FISH Probe
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Catalog: |
GFFP-SBF2/MDM2-10469 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SBF2-MDM2 Gene Fusion FISH Probecan detect the fusion of SBF2 and MDM2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SBF2-MDM2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
MDM2 Proto-oncogene |
Gene Summary 1 |
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12q15 |
Coordinates 1 |
This gene maps to 69201970-69239212 in GRCh37 coordinates. |
Gene Name 2 |
SET Binding Factor 2 |
Gene Summary 2 |
This gene encodes a pseudophosphatase and member of the myotubularin-related protein family. This gene maps within the CMT4B2 candidate region of chromosome 11p15 and mutations in this gene have been associated with Charcot-Marie-Tooth Disease, type 4B2. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11p15.4 |
Coordinates 2 |
This gene maps to 9800213-10315754 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SBF2/MDM2-10469-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SBF2/MDM2-10469-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SBF2/MDM2-10469-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SBF2/MDM2-10469-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SBF2/MDM2-10469-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SBF2/MDM2-10469-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SBF2/MDM2-10469-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SBF2/MDM2-10469-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SBF2/MDM2-10469-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SBF2/MDM2-10469-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SBF2/MDM2-10469-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SBF2/MDM2-10469-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SBF2/MDM2-10469-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SBF2/MDM2-10469-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SBF2/MDM2-10469-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SBF2/MDM2-10469-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SBF2/MDM2-10469-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SBF2/MDM2-10469-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SBF2/MDM2-10469-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SBF2/MDM2-10469-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SBF2/MDM2-10469-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SBF2/MDM2-10469-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SBF2/MDM2-10469-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SBF2/MDM2-10469-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SBF2/MDM2-10469-AQAQ |
467nm;467nm |
418nm;418nm |
|
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