SASH1-PLN Gene Fusion FISH Probe
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| Catalog: |
GFFP-SASH1/PLN-10495 |
| Classification: |
Gene Fusion FISH Probes |
| Description: |
The SASH1-PLN Gene Fusion FISH Probecan detect the fusion of SASH1 and PLN genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Category: |
Gene Fusion FISH Probes |
| Application: |
SASH1-PLN Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name 1 |
Phospholamban |
| Gene Summary 1 |
The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy. [provided by RefSeq, Apr 2016] |
| Chromosome 1 |
Chromosome 6 |
| Locus 1 |
6q22.31 |
| Coordinates 1 |
This gene maps to 118869441-118881587 in GRCh37 coordinates. |
| Gene Name 2 |
SAM And SH3 Domain Containing 1 |
| Gene Summary 2 |
This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients. [provided by RefSeq, Oct 2016] |
| Chromosome 2 |
Chromosome6 |
| Locus 2 |
6q24.3-q25.1 |
| Coordinates 2 |
This gene maps to 148663728-148873184 in GRCh37 coordinates. |
| Associated Diseases |
Uterine Corpus Endometrial Carcinoma |
| Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
RE; RE
|
GFFP-SASH1/PLN-10495-RERE |
599nm;599nm |
580nm;580nm |
|
| 2 |
RE; OR
|
GFFP-SASH1/PLN-10495-REOR |
599nm;573nm |
580nm;548nm |
|
| 3 |
RE; GO
|
GFFP-SASH1/PLN-10495-REGO |
599nm;551nm |
580nm;525nm |
|
| 4 |
RE; GR
|
GFFP-SASH1/PLN-10495-REGR |
599nm;515nm |
580nm;491nm |
|
| 5 |
RE; AQ
|
GFFP-SASH1/PLN-10495-REAQ |
599nm;467nm |
580nm;418nm |
|
| 6 |
OR; RE
|
GFFP-SASH1/PLN-10495-ORRE |
573nm;599nm |
548nm;580nm |
|
| 7 |
OR; OR
|
GFFP-SASH1/PLN-10495-OROR |
573nm;573nm |
548nm;548nm |
|
| 8 |
OR; GO
|
GFFP-SASH1/PLN-10495-ORGO |
573nm;551nm |
548nm;525nm |
|
| 9 |
OR; GR
|
GFFP-SASH1/PLN-10495-ORGR |
573nm;515nm |
548nm;491nm |
|
| 10 |
OR; AQ
|
GFFP-SASH1/PLN-10495-ORAQ |
573nm;467nm |
548nm;418nm |
|
| 11 |
GO; RE
|
GFFP-SASH1/PLN-10495-GORE |
551nm;599nm |
525nm;580nm |
|
| 12 |
GO; OR
|
GFFP-SASH1/PLN-10495-GOOR |
551nm;573nm |
525nm;548nm |
|
| 13 |
GO; GO
|
GFFP-SASH1/PLN-10495-GOGO |
551nm;551nm |
525nm;525nm |
|
| 14 |
GO; GR
|
GFFP-SASH1/PLN-10495-GOGR |
551nm;515nm |
525nm;491nm |
|
| 15 |
GO; AQ
|
GFFP-SASH1/PLN-10495-GOAQ |
551nm;467nm |
525nm;418nm |
|
| 16 |
GR; RE
|
GFFP-SASH1/PLN-10495-GRRE |
515nm;599nm |
491nm;580nm |
|
| 17 |
GR; OR
|
GFFP-SASH1/PLN-10495-GROR |
515nm;573nm |
491nm;548nm |
|
| 18 |
GR; GO
|
GFFP-SASH1/PLN-10495-GRGO |
515nm;551nm |
491nm;525nm |
|
| 19 |
GR; GR
|
GFFP-SASH1/PLN-10495-GRGR |
515nm;515nm |
491nm;491nm |
|
| 20 |
GR; AQ
|
GFFP-SASH1/PLN-10495-GRAQ |
515nm;467nm |
491nm;418nm |
|
| 21 |
AQ; RE
|
GFFP-SASH1/PLN-10495-AQRE |
467nm;599nm |
418nm;580nm |
|
| 22 |
AQ; OR
|
GFFP-SASH1/PLN-10495-AQOR |
467nm;573nm |
418nm;548nm |
|
| 23 |
AQ; GO
|
GFFP-SASH1/PLN-10495-AQGO |
467nm;551nm |
418nm;525nm |
|
| 24 |
AQ; GR
|
GFFP-SASH1/PLN-10495-AQGR |
467nm;515nm |
418nm;491nm |
|
| 25 |
AQ; AQ
|
GFFP-SASH1/PLN-10495-AQAQ |
467nm;467nm |
418nm;418nm |
|
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