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SAFB-RFX2 Gene Fusion FISH Probe

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Catalog: GFFP-SAFB/RFX2-10526
Classification: Gene Fusion FISH Probes
Description: The SAFB-RFX2 Gene Fusion FISH Probecan detect the fusion of SAFB and RFX2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SAFB-RFX2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Regulatory Factor X2
Gene Summary 1 This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 19
Locus 1 19p13.3
Coordinates 1 This gene maps to 5993174-6110664 in GRCh37 coordinates.
Gene Name 2 Scaffold Attachment Factor B
Gene Summary 2 This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]
Chromosome 2 Chromosome19
Locus 2 19p13.3
Coordinates 2 This gene maps to 5623045-5668489 in GRCh37 coordinates.
Associated Diseases Ovarian Serous Cystadenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SAFB/RFX2-10526-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SAFB/RFX2-10526-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SAFB/RFX2-10526-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SAFB/RFX2-10526-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SAFB/RFX2-10526-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SAFB/RFX2-10526-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SAFB/RFX2-10526-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SAFB/RFX2-10526-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SAFB/RFX2-10526-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SAFB/RFX2-10526-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SAFB/RFX2-10526-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SAFB/RFX2-10526-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SAFB/RFX2-10526-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SAFB/RFX2-10526-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SAFB/RFX2-10526-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SAFB/RFX2-10526-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SAFB/RFX2-10526-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SAFB/RFX2-10526-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SAFB/RFX2-10526-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SAFB/RFX2-10526-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SAFB/RFX2-10526-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SAFB/RFX2-10526-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SAFB/RFX2-10526-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SAFB/RFX2-10526-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SAFB/RFX2-10526-AQAQ 467nm;467nm 418nm;418nm

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